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Product Info Summary
| SKU: | PA1131 |
|---|---|
| Size: | 100μg/vial |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-OPCML Antibody
View all OBCAM/OPCML Antibodies
SKU/Catalog Number
PA1131
Size
100μg/vial
Form
Lyophilized
Description
Boster Bio Anti-OPCML Antibody catalog # PA1131. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-OPCML Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1131)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human OPCML (294-312aa YTCVATNKLGNTNASITLY), identical to the related rat and mouse sequences.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross Reactivity
No cross reactivity with other proteins
Reactive Species
PA1131 is reactive to OPCML in Human, Mouse, Rat
Applications
PA1131 is guaranteed for IHC, WB Boster Guarantee
Background of OBCAM/OPCML
Opioid-binding protein/cell adhesion molecule-like (OPCML), (also called opioid-binding cell adhesion molecule (OBCAM). OPCML is a member of the IgLON family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules, as an excellent candidate for the 11q25 ovarian cancer TSG in EOC. The OPCML gene comprises 7 exons, spans approximately 600 kb, and is transcribed from telomere to centromere . And due to the lack of transmembrane domains necessary for signal transduction, it is improbable that OBCAM acts independently as an opioid receptor; more likely, it plays an important accessory role in opioid receptor function.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists world wide.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Validation Images & Assay Conditions
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Anti-OPCML antibody, PA1131, Western blotting
WB: Rat Brain Tissue Lysate
Click image to see more details
Anti-OPCML antibody, PA1131, IHC(P)
IHC(P): Human Mammary Cancer Tissue
Protein Target Info & Infographic
Gene/Protein Information For OPCML (Source: Uniprot.Org, NCBI)
Uniprot ID
Q14982
Gene ID
4978
Gene Name
OPCML
Full Name
Opioid-binding protein/cell adhesion molecule
Weight
38.008kDa
Superfamily
immunoglobulin superfamily
Alternative Names
IgLON family member 1; IGLON1opioid-binding protein/cell adhesion molecule-like; OBCAM; OBCAMopiate binding-cell adhesion molecule; OPCM; OPCML; opioid binding protein/cell adhesion molecule-like preprotein; opioid binding protein/cell adhesion molecule-like; Opioid-binding cell adhesion molecule; opioid-binding protein/cell adhesion molecule OPCML IGLON1, OBCAM, OPCM opioid binding protein/cell adhesion molecule like opioid-binding protein/cell adhesion molecule|IgLON family member 1|opioid binding protein/cell adhesion molecule-like preprotein
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".For more info on OPCML, check out the OPCML Infographic
We have 30,000+ of these available, one for each gene! check them out.
In this infographic you will see the following information for OPCML: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]
Specific Publications For Anti-OPCML Antibody (PA1131)
PA1131 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Wang L, Zhu Js, Song Mq, Chen Gq, Chen Jl. World J Gastroenterol. 2006 Nov 21;12(43):6949-54. Comparison Of Gene Expression Profiles Between Primary Tumor And Metastatic Lesions In Gastric Cancer Patients Using Laser Microdissection And Cdna Micro...
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Customer Reviews
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Customer Q&As
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6 Customer Q&As for Anti-OPCML Antibody
Question
Is a blocking peptide available for product anti-OPCML antibody (PA1131)?
Verified Customer
Verified customer
Asked: 2019-08-22
Answer
We do provide the blocking peptide for product anti-OPCML antibody (PA1131). If you would like to place an order for it please contact [email protected] and make a special request.
Boster Scientific Support
Answered: 2019-08-22
Question
Is this PA1131 anti-OPCML antibody reactive to the isotypes of OPCML?
Verified Customer
Verified customer
Asked: 2019-07-29
Answer
The immunogen of PA1131 anti-OPCML antibody is A synthetic peptide corresponding to a sequence at the C-terminus of human OPCML(294-312aa YTCVATNKLGNTNASITLY), identical to the related rat and mouse sequences. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2019-07-29
Question
Does anti-OPCML antibody PA1131 work for WB with brain fetal brain?
Verified Customer
Verified customer
Asked: 2019-05-21
Answer
According to the expression profile of brain fetal brain, OPCML is highly expressed in brain fetal brain. So, it is likely that anti-OPCML antibody PA1131 will work for WB with brain fetal brain.
Boster Scientific Support
Answered: 2019-05-21
Question
We are currently using anti-OPCML antibody PA1131 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on dog tissues as well?
Verified Customer
Verified customer
Asked: 2018-11-22
Answer
The anti-OPCML antibody (PA1131) has not been validated for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2018-11-22
Question
Thanks for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for brain fetal brain using anti-OPCML antibody PA1131. Let me know if you need anything else.
A. Wu
Verified customer
Asked: 2018-11-19
Answer
We appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2018-11-19
Question
See attached the WB image, lot number and protocol we used for brain fetal brain using anti-OPCML antibody PA1131. Please let me know if you require anything else.
Verified Customer
Verified customer
Asked: 2018-01-08
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2018-01-08
