Anti-Phospho-PIP5KIII (S307) PIKFYVE Antibody

Product Name

Anti-Phospho-PIP5KIII (S307) PIKFYVE Antibody

View all PIKFyve/PIP5K3 Antibodies

SKU/Catalog Number

A02638S307

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Phospho-PIP5KIII (S307) PIKFYVE Antibody catalog # A02638S307. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Phospho-PIP5KIII (S307) PIKFYVE Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02638S307)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human PIP5KIII around the phosphorylation site of S307.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02638S307 is reactive to Pikfyve in Human, Mouse, Rat

Applications

A02638S307 is guaranteed for ELISA, IF, IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

236.877kDa

Background of PIKFyve/PIP5K3

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.

Ota T., Nat. Genet. 36:40-45(2004).
Sbrissa D., J. Biol. Chem. 277:6073-6079(2002).
Brill L.M., Anal. Chem. 76:2763-2772(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For Pikfyve (Source: Uniprot.org, NCBI)

Alternative Names

1-phosphatidylinositol-3-phosphate 5-kinase; EC 2.7.1.150; FAB1; FLJ37746; FYVE finger-containing phosphoinositide kinase; KIAA0981CFD; MGC40423; p235; Phosphatidylinositol-3-phosphate 5-kinase type III; Phosphatidylinositol-3-phosphate 5-kinase; phosphoinositide kinase, FYVE finger containing; PIKFyve; PIP5K; PIP5K3; PIP5K3FAB1; PIPkin-III; Type III PIP kinase; type III Pikfyve|5230400C17Rik, P, Pip, Pip5k, Pip5k3, Pipk5k3, PipkIII, p235|phosphoinositide kinase, FYVE type zinc finger containing|1-phosphatidylinositol 3-phosphate 5-kinase|FYVE finger-containing phosphoinositide kinase|PIPkin-III|PtdIns(4)P-5-kinase|phosphatidylinositol 3-phosphate 5-kinase type III|phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III|phosphatidylinositol-4-phosphate 5-kinase, type III|phosphoinositide kinase, FYVE finger containing|serine-protein kinase PIKFYVE|type III PIP kinase

For more info on Pikfyve, check out the Pikfyve Infographic

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In this infographic, you will see the following information for Pikfyve: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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