Product Info Summary
SKU: | A09740 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-ZHX3 Antibody
SKU/Catalog Number
A09740
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ZHX3 Antibody catalog # A09740. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ZHX3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09740)
Host
Rabbit
Contents
Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human RFWD3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09740 is reactive to ZHX3 in Human, Mouse, Rat
Applications
A09740 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
104.658kDa
Background of ZHX3
E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Ota T., Nat. Genet. 36:40-45(2004).
Matsuoka S., Science 316:1160-1166(2007).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-2000 ELISA 1:5000-20000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For ZHX3 (Source: Uniprot.org, NCBI)
Gene Name
ZHX3
Full Name
Zinc fingers and homeoboxes protein 3
Weight
104.658kDa
Superfamily
ZHX family
Alternative Names
FLJ93221; SP38; zona pellucida binding protein; zona pellucida-binding protein 1; ZPBP1zona pellucida binding protein 1 ZHX3 TIX1 zinc fingers and homeoboxes 3 zinc fingers and homeoboxes protein 3|triple homeobox 1|triple homeobox protein 1|zinc finger and homeodomain protein 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ZHX3, check out the ZHX3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ZHX3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ZHX3 Antibody (A09740)
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No publications found for A09740
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