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- Table of Contents
ANGPTL4 Antibodies
AND ANGPTL4 ELISA kits, ANGPTL4 Proteins
Many biological assays use antibodies to detect ANGPTL4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ANGPTL4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ANGPTL4 antibodies...
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ANGPTL4 Infographic by Boster Bio
All ANGPTL4 Products
Product
Figures
Specificity
Applications
Price
Human ANGPTL4 / Angiopoietin Like 4 / ARP4 ELISA Kit PicoKine®
2 Citations 4 Q&As
Human
ELISA
$499
Cat # EK0960
96 wells/kit, with removable strips.
Cat # EK0960
96 wells/kit, with removable strips.
Human, Rat
WB
$370
Cat # PA1435
100 μg/vial
Cat # PA1435
100 μg/vial
Anti-Angiopoietin-like 4/ANGPTL4 Antibody Picoband®
3 Citations 6 Q&As
Human
ELISA, IHC, WB
$370
Cat # A01147
100 μg/vial
Cat # A01147
100 μg/vial
Human
ELISA
$499
Cat # FEK0960
96 wells/kit, with removable strips.
Cat # FEK0960
96 wells/kit, with removable strips.
Human
$628
Cat # LS051129
20 µg, 100 µg
Cat # LS051129
20 µg, 100 µg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01147
100 μg
Cat # M01147
100 μg
Human
ELISA
$500
Cat # EZ0960
5 plates/kit
Cat # EZ0960
5 plates/kit
ANGPTL4 Overview
Facts about Angiopoietin-related protein 4.
Angiopoietin-related protein 4 (ANGPTL4)
May act as a regulator of angiogenesis and regulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage.
May exert a protective role on endothelial cells through an endocrine action. It's directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity.
Gene Information
| Human | |
|---|---|
| Gene Name: | ANGPTL4 |
| Uniprot: | Q9BY76 |
| Entrez: | 51129 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Angiopoietin like Protein 4; angiopoietin-like 4; Angiopoietin-like Protein 4; ANGPTL4; ARP4fasting-induced adipose factor; FIAF; FIAFhepatic angiopoietin-related protein; Hepatic fibrinogen/angiopoietin-related protein; HFARP; HFARPANGPTL2; NL2; peroxisome proliferator-activated receptor (PPAR) gamma inducedangiopoietin-related protein; PGAR; PGARangiopoietin-related protein 4; pp1158; PPARG angiopoietin related protein
Molecular Weight
Mass (kDA):
45.214 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.2 |
| Sequence: | 19; NC_000019.10 (8364129..8374373) |
Tissue Specificity
Expressed at high levels in the placenta, heart, liver, muscle, pancreas and lung but expressed poorly in the brain and kidney.
Subcellular Localizations
Secreted. Secreted, extracellular space, extracellular matrix. The unprocessed form interacts with the extracellular matrix (PubMed:17068295, PubMed:21398697). This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4 (Probable).
Diseases
- Malignant Neoplasms
- Neoplasms
- Obesity
- Tumor Angiogenesis
- Hypoxia
- Neoplasm Metastasis
- Diabetes Mellitus
- Inflammation
- Insulin Resistance
- Pathologic Neovascularization
- Carcinoma
- Atherosclerosis
Interacting Proteins
- ITGB1
- ITGB5
Pathways
- Angiogenesis
- Secretion
- Cell Proliferation
- Cell Migration
- Energy Homeostasis
- Pathogenesis
- Cell Growth
- Glucose Homeostasis
- Inflammatory Response
- Response To Hypoxia
- Lipid Homeostasis
- Transport
- Anoikis
PTMs
- Phosphorylation
- Oxidation
- Cleavage
Research Areas
- Apoptosis
- Cancer
- Hypoxia
- Lipid and Metabolism
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANGPTL4
bosterbio.com/bosterbio-gene-info-cards/ANGPTL4
References
PMID: 10698685 by Kim I., et al. Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis.
PMID: 10866690 by Yoon J.C., et al. Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation.
2 Publications of Boster ANGPTL4 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.lfs.2018.11.062, Effects of sprint interval or combined aerobic and resistance training on myokin...
- PubMed ID: -, Zhao,J.,Liu,J.,Wu,N.,Zhang,H.,Zhang,S.,Li,L.,& Wang,M.(2020).ANGPTL4 overexpress...
*More publications can be found for each product on its corresponding product page