Angiopoietin-related protein 4 (ANGPTL4)

May act as a regulator of angiogenesis and regulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage.

May exert a protective role on endothelial cells through an endocrine action. It's directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity.