Anoctamin-2 Antibodies

AND ANO2 ELISA kits, Anoctamin-2 Proteins

Many biological assays use antibodies to detect Anoctamin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Anoctamin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Anoctamin-2 antibodies...

We validate the specificity of these antibodies to Anoctamin-2 by testing them on tissues known to express ANO2 positively and negatively. Browse below to find the ANO2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ANO2 Infographic by Boster Bio

All ANO2 Products

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Figures

Specificity

Applications

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Anti-TMEM16B ANO2 Antibody

Western blot analysis of TMEM16B in human small intestine tissue lysate with TMEM16B antibody at (A) 1 and (B) 2 μg/mL

Immunohistochemistry of TMEM16B in human brain tissue with FRMPD4 antibody at 5 μg/mL

Immunofluorescence of TMEM16B in Human Brain cells with TMEM16B antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A04801
0.1 mg

TMEM16B (ANO2) (NM_020373) Human Over-expression Lysate

Human

$960
Cat # LS057101
20 µg, 100 µg

Anti-ANO2 Antibody

Human, Mouse, Rat

ELISA, IP, IF, IHC, WB

$370
Cat # A04801-1
100 μl/vial

ANO2 Overview

Facts about Anoctamin-2.

ANO2 3D structure. Source: alphafold

Anoctamin-2 (ANO2)

Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to a rise in calcium entry that triggers CaCC current which amplifies the depolarization of the OSR cells, ANO2 appears to be the inherent chloride channel involved in this procedure.

May mediate light perception amplification in retina. .

Gene Information

Human
Gene Name:	ANO2
Uniprot:	Q9NQ90
Entrez:	57101

Family

Belongs to:

anoctamin family

Alternative Names

Anoctamin-2

Molecular Weight

Mass (kDA):
113.969 kDA

Genomic Context


Human

Location:	12p13.31
Sequence:	12; NC_000012.12 (5560241..5948790, complement)

Tissue Specificity

Retina, especially in the photoreceptor synaptic terminals.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Interacting Proteins

DLG1

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANO2

References

PMID: 19474308 by Stoehr H., et al. TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals.

PMID: 20056604 by Schreiber R., et al. Expression and function of epithelial anoctamins.