Anoctamin-2 (ANO2)

Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to a rise in calcium entry that triggers CaCC current which amplifies the depolarization of the OSR cells, ANO2 appears to be the inherent chloride channel involved in this procedure.

May mediate light perception amplification in retina. .