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- Table of Contents
Aquaporin-3 Antibodies
AND AQP3 ELISA kits, Aquaporin-3 Proteins
Many biological assays use antibodies to detect Aquaporin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Aquaporin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Aquaporin-3 antibodies...
Designing a Western blot for Aquaporin-3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AQP3 Western Blot GuideAQP3 Video by Boster Bio
All AQP3 Products
Product
Figures
Specificity
Applications
Price
Anti-Aquaporin 3/AQP3 Antibody Picoband®
13 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PA1488
100 μg/vial
Cat # PA1488
100 μg/vial
AQP3 Overview
Facts about Aquaporin-3.
Aquaporin-3 (AQP3)
Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays a significant role in regulating SC (stratum corneum) and epidermal glycerol content.
Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may be a water and urea exit mechanism in antidiuresis in collecting duct cells.
Gene Information
| Human | |
|---|---|
| Gene Name: | AQP3 |
| Uniprot: | Q92482 |
| Entrez: | 360 |
Family
| Belongs to: |
|---|
| MIP/aquaporin (TC 1.A.8) family |
Alternative Names
AQP-3; aquaglyceroporin-3; aquaporin 3 (GIL blood group); aquaporin 3 (Gill blood group); aquaporin 3; aquaporin-3; GIL; Gill blood group
Molecular Weight
Mass (kDA):
31.544 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p13.3 |
| Sequence: | 9; NC_000009.12 (33441154..33447596, complement) |
Tissue Specificity
Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Diseases
- Disease Of Adrenal Medulla
- Diabetes Mellitus
- Edema
- Malignant Neoplasms
- Neoplasms
- Dehydration
- Nephrogenic Diabetes Insipidus
- Polyuria
- Carcinoma
- Deprivation Of Water
- Kidney Diseases
- Adenocarcinoma
Pathways
- Transport
- Water Transport
- Localization
- Secretion
- Glycerol Transport
- Excretion
- Water Homeostasis
- Fluid Transport
- Cell Migration
- Cell Proliferation
- Wound Healing
- Cellular Localization
- Reverse Transcription
PTMs
- Phosphorylation
- Glycosylation
Research Areas
- Membrane Trafficking and Chaperones
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AQP3
bosterbio.com/bosterbio-gene-info-cards/AQP3
References
PMID: 7558005 by Ishibashi K., et al. Structure and chromosomal localization of a human water channel (AQP3) gene.
PMID: 12239222 by Roudier N., et al. AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL.
2 Publications of Boster Aquaporin-3 Antibodies & ELISA Kits
- PubMed ID: 26261083, Expression pattern of aquaporins in patients with primary nephrotic syndrome wit...
- PubMed ID: 28894278, Shin SY, Lee DH, Gil HN, Kim BS, Choe JS, Kim JB, Lee YH, Lim Y. Sci Rep. 2017 S...
*More publications can be found for each product on its corresponding product page