Myotonin-protein kinase Antibodies

AND DMPK ELISA kits, Myotonin-protein kinase Proteins

Many biological assays use antibodies to detect Myotonin-protein kinase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myotonin-protein kinase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myotonin-protein kinase antibodies...

We validate the specificity of these antibodies to Myotonin-protein kinase by testing them on tissues known to express DMPK positively and negatively. Browse below to find the DMPK antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DMPK Infographic by Boster Bio

All DMPK Products

Product

Figures

Specificity

Applications

Price

Anti-Myotonin-protein kinase DMPK Antibody

3 Q&As

Human

$399
Cat # A00797
100μl

DMPK Colorimetric Cell-Based ELISA

Human

ELISA

$480
Cat # EKC1781
1 kit, containing one 96-well plate and all necessary reagents

Anti-DMPK (R30) Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A00797-1
100ul

Dystrophia myotonica protein kinase (DMPK) (NM_001081562) Human Recombinant Protein

$1249
Cat # PROTQ09013
20 µg

Dystrophia myotonica protein kinase (DMPK) (NM_004409) Human Over-expression Lysate

Human

$628
Cat # LS001760
100 µg

DMPK Overview

Facts about Myotonin-protein kinase.

DMPK 3D structure. Source: alphafold

Myotonin-protein kinase (DMPK)

Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte survival and differentiation by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes.

May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to modulate myosin phosphorylation. Also vital to the modulation of cardiac contractility and to the maintenance of appropriate cardiac conduction activity likely through the regulation of cellular calcium homeostasis.

Gene Information

Human
Gene Name:	DMPK
Uniprot:	Q09013
Entrez:	1760

Family

Belongs to:

protein kinase superfamily

Alternative Names

DM1; DM1PK; DMK; DMKEC 2.7.11.1; DM-kinase; DMmyotonin protein kinase A; DMPK; dystrophia myotonica-protein kinase; MDPK; MDPKDM protein kinase; MT-PK; MT-PKmyotonic dystrophy associated protein kinase; Myotonic dystrophy protein kinase; myotonin-protein kinase; thymopoietin homolog

Molecular Weight

Mass (kDA):
69.385 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (45769709..45782490, complement)

Tissue Specificity

Most isoforms are expressed in many tissues including heart, skeletal muscle, liver and brain, except for isoform 2 which is only found in the heart and skeletal muscle, and isoform 14 which is only found in the brain, with high levels in the striatum, cerebellar cortex and pons.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side. Nucleus outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. Mitochondrion outer membrane; Single-pass type IV membrane protein. Sarcoplasmic reticulum membrane. Cell membrane. Cytoplasm, cytosol. Localizes to sarcoplasmic reticulum membranes of cardiomyocytes.; [Isoform 1]: Mitochondrion membrane.; [Isoform 3]: Mitochondrion membrane.