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- Table of Contents
Transcription factor E2F1 Antibodies
AND E2F1 ELISA kits, Transcription factor E2F1 Proteins
Many biological assays use antibodies to detect Transcription factor E2F1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor E2F1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor E2F1 antibodies...
Designing a Western blot for Transcription factor E2F1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the E2F1 Western Blot GuideE2F1 Infographic by Boster Bio
All E2F1 Products
Product
Figures
Specificity
Applications
Price
Anti-E2F1 Rabbit Monoclonal Antibody
4 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00257
100 μl
Cat # M00257
100 μl
Anti-E2F1 Antibody Picoband®
2 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00257-2
100 μg/vial
Cat # A00257-2
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # PA1560
100 μg/vial
Cat # PA1560
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00259
100 μl/vial
Cat # M00259
100 μl/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00257-1
20μL, 40μL, 100μL, 200μL
Cat # M00257-1
20μL, 40μL, 100μL, 200μL
Human, Mouse
ELISA
$540
Cat # EKC2029
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2029
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$480
Cat # EKC1178
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1178
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A00257-1
100ul
Cat # A00257-1
100ul
E2F1 Overview
Facts about Transcription factor E2F1.
Transcription factor E2F1 (E2F1)
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase.
E2F1 binds preferentially RB1 in a cell-cycle dependent way. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
Gene Information
| Human | |
|---|---|
| Gene Name: | E2F1 |
| Uniprot: | Q01094 |
| Entrez: | 1869 |
Family
| Belongs to: |
|---|
| E2F/DP family |
Alternative Names
E2F transcription factor 1; E2F1; E2F-1; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; Retinoblastoma-associated protein 1; Retinoblastoma-binding protein 3; transcription factor E2F1
Molecular Weight
Mass (kDA):
46.92 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20q11.22 |
| Sequence: | 20; NC_000020.11 (33675477..33686385, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Retinoblastoma
- Carcinoma
- Cell Transformation, Neoplastic
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Hyperplasia
- Malignant Paraganglionic Neoplasm
- Growth Arrest
- Carcinogenesis
- Malignant Neoplasm Of Prostate
Interacting Proteins
- BTG3
- CDK7
- CDK8
- DDB2
- HDAC1
- KAT2A
- MCPH1
- NCOR2
- PARP1
- PAWR
Pathways
- Cell Cycle
- Cell Proliferation
- S Phase
- Cell Growth
- Cell Death
- Cell Cycle Arrest
- Dna Replication
- Induction Of Apoptosis
- Localization
- Dna Repair
- G1 Phase
- Methylation
- Senescence
PTMs
- Phosphorylation
- Methylation
- Acetylation
- Dephosphorylation
- Cleavage
- Ubiquitination
- Demethylation
Research Areas
- Apoptosis
- Cancer
- Cell Cycle and Replication
- Phospho-Specific
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/E2F1
bosterbio.com/bosterbio-gene-info-cards/E2F1
References
PMID: 1638634 by Helin K., et al. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F.
PMID: 1638635 by Kaelin W.G. Jr., et al. Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties.
6 Publications of Boster Transcription factor E2F1 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.biopha.2017.04.044, Cisatracurium-induced proliferation impairment and death of colorectal cancer ce...
- PubMed ID: 10.1007/s00240-006-0063-3, Deregulation of the p16-cyclin D1/cyclin-dependent kinase 4–retinoblastoma pat...
- PubMed ID: 26378521, GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling P...
- PubMed ID: 20049626, Wang Py, Li Yj, Zhang S, Li Zl, Yue Z, Xie N, Xie Sy. Mol Cell Biochem. 2010 Jun...
- PubMed ID: 20428827, Xie Sy, Li Yj, Wang Py, Jiao F, Zhang S, Zhang Wj. Oncol Rep. 2010 Jun;23(6):169...
- PubMed ID: 25431082, Zhou R, Lu Z, Liu K, Guo J, Liu J, Zhou Y, Yang J, Mi M, Xu H. Curr Cancer Drug ...
*More publications can be found for each product on its corresponding product page