Ephrin type-B receptor 6 (EPHB6)

Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2.

Modulates cell adhesion and migration by exerting both negative and positive effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.