Glycine N-acyltransferase Antibodies

AND GLYAT ELISA kits, Glycine N-acyltransferase Proteins

Many biological assays use antibodies to detect Glycine N-acyltransferase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Glycine N-acyltransferase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Glycine N-acyltransferase antibodies...

We validate the specificity of these antibodies to Glycine N-acyltransferase by testing them on tissues known to express GLYAT positively and negatively. Browse below to find the GLYAT antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GLYAT Infographic by Boster Bio

All GLYAT Products

Product

Figures

Specificity

Applications

Price

Human GLYAT Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ6IB77
Starting from 10ug

Anti-GLYAT Mouse Monoclonal Antibody [Clone ID: OTI4D1]

Human

IHC, WB

$523
Cat # M09506
100 µl

GLYAT (NM_201648) Human Over-expression Lysate

Human

$628
Cat # LS010249
100 µg

GLYAT Overview

Facts about Glycine N-acyltransferase.

GLYAT 3D structure. Source: alphafold

Glycine N-acyltransferase (GLYAT)

Mitochondrial acyltransferase which transports an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a taste for benzoyl-CoA over phenylacetyl-CoA as acyl donors.

Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid. .

Gene Information

Human
Gene Name:	GLYAT
Uniprot:	Q6IB77
Entrez:	10249

Family

Belongs to:

glycine N-acyltransferase family

Alternative Names

ACGNATAAc; Acyl-CoA:glycine N-acyltransferase; Aralkyl acyl-CoA N-acyltransferase; Aralkyl acyl-CoA:amino acid N-acyltransferase; aralkyl-CoA N-acyltransferase; CATEC 2.3.1.13; GATHRP-1(CLP); glycine N-acyltransferase; glycine-N-acyltransferase

Molecular Weight

Mass (kDA):
33.924 kDA

Genomic Context


Human

Location:	11q12.1
Sequence:	11; NC_000011.10 (58708757..58731974, complement)

Tissue Specificity

Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers.

Subcellular Localizations

Mitochondrion.

Diseases

Liver Diseases
Liver Carcinoma
Depressive Disorder
Pain
Liver Neoplasms
Inflammation
Dysequilibrium Syndrome
Hypokinesia

Carcinogenesis
Carcinoma

Interacting Proteins

KRTAP10-8
NOTCH2NL

Pathways

Transport
Cell Migration
Cellular Localization
Aging
Localization
Conjugation

PTMs

Amination

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GLYAT

References

PMID: 10630424 by van der Westhuizen F.H., et al. The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase.

PMID: 22475485 by Matsuo M., et al. Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma.