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- Table of Contents
Facts about Golgi phosphoprotein 3.
May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion.
Human | |
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Gene Name: | GOLPH3 |
Uniprot: | Q9H4A6 |
Entrez: | 64083 |
Belongs to: |
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GOLPH3/VPS74 family |
Coat protein GPP34; FLJ90675; golgi phosphoprotein 3 (coat-protein); Golgi phosphoprotein 3; golgi protein; golgi-associated protein; GOPP1; GPP34coat-protein; MIDASgolgi peripheral membrane protein 1, 34 kDa; Mitochondrial DNA absence factor
Mass (kDA):
33.811 kDA
Human | |
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Location: | 5p13.3 |
Sequence: | 5; NC_000005.10 (32124711..32174319, complement) |
Detected in muscle fibers of patients with mitochondrial diseases; not detected in normal muscle fibers.
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion intermembrane space. Cell membrane. Endosome. Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes.
PMID: 11042173 by Bell A.W., et al. Proteomics characterization of abundant Golgi membrane proteins.
PMID: 16263763 by Nakashima-Kamimura N., et al. MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction.