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Golgi phosphoprotein 3 Antibodies
AND GOLPH3 ELISA kits, Golgi phosphoprotein 3 Proteins
Many biological assays use antibodies to detect Golgi phosphoprotein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Golgi phosphoprotein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Golgi phosphoprotein 3 antibodies...
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GOLPH3 Infographic by Boster Bio
All GOLPH3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A01333-1
100 μg/vial
Cat # A01333-1
100 μg/vial
GOLPH3 Overview
Facts about Golgi phosphoprotein 3.
Golgi phosphoprotein 3 (GOLPH3)
Phosphatidylinositol-4-phosphate-binding protein which links Golgi membranes into the cytoskeleton and may take part in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus.
May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion.
Gene Information
| Human | |
|---|---|
| Gene Name: | GOLPH3 |
| Uniprot: | Q9H4A6 |
| Entrez: | 64083 |
Family
| Belongs to: |
|---|
| GOLPH3/VPS74 family |
Alternative Names
Coat protein GPP34; FLJ90675; golgi phosphoprotein 3 (coat-protein); Golgi phosphoprotein 3; golgi protein; golgi-associated protein; GOPP1; GPP34coat-protein; MIDASgolgi peripheral membrane protein 1, 34 kDa; Mitochondrial DNA absence factor
Molecular Weight
Mass (kDA):
33.811 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5p13.3 |
| Sequence: | 5; NC_000005.10 (32124711..32174319, complement) |
Tissue Specificity
Detected in muscle fibers of patients with mitochondrial diseases; not detected in normal muscle fibers.
Subcellular Localizations
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion intermembrane space. Cell membrane. Endosome. Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes.
Diseases
- Malignant Neoplasms
- Neoplasms
- Cell Transformation, Neoplastic
- Neoplasm Metastasis
- Melanoma
- Solid Tumor
- Malignant Neoplasm Of Breast
- Glioma
- Hepatitis
- Hepatitis C
- Malignant Neoplasm Of Lung
- Malignant Neoplasm Of Prostate
Interacting Proteins
- ARL6IP1
- GCNT1
- MYO18A
- XRCC5
Pathways
- Transport
- Localization
- Golgi Localization
- Secretion
- Pathogenesis
- Cell Adhesion
- Virion Assembly
- Secretory Pathway
- Cell Proliferation
- Glycosylation
- Response To Oxidative Stress
- Reverse Transcription
- Lipid Homeostasis
PTMs
- Phosphorylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GOLPH3
bosterbio.com/bosterbio-gene-info-cards/GOLPH3
References
PMID: 11042173 by Bell A.W., et al. Proteomics characterization of abundant Golgi membrane proteins.
PMID: 16263763 by Nakashima-Kamimura N., et al. MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction.