HS3ST1 Antibodies

AND HS3ST1 ELISA kits, HS3ST1 Proteins

Many biological assays use antibodies to detect HS3ST1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HS3ST1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HS3ST1 antibodies...

We validate the specificity of these antibodies to HS3ST1 by testing them on tissues known to express HS3ST1 positively and negatively. Browse below to find the HS3ST1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HS3ST1 Infographic by Boster Bio

All HS3ST1 Products

Product

Figures

Specificity

Applications

Price

HS3ST1 (NM_005114) Human Recombinant Protein

$1249
Cat # PROTO14792
20 µg

HS3ST1 (NM_005114) Human Over-expression Lysate

Human

$628
Cat # LS009957
100 µg

HS3ST1 Overview

Facts about Heparan sulfate glucosamine 3-O-sulfotransferase 1.

HS3ST1 3D structure. Source: alphafold

Heparan sulfate glucosamine 3-O-sulfotransferase 1 (HS3ST1)

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to place 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact).

This modification is a vital step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. .

Gene Information

Human
Gene Name:	HS3ST1
Uniprot:	O14792
Entrez:	9957

Family

Belongs to:

sulfotransferase 1 family

Alternative Names

3OST; 3OST1; 3-OST-1; 3OST1Heparan sulfate 3-O-sulfotransferase 1; EC 2.8.2; EC 2.8.2.23; h3-OST-1; heparan sulfate (glucosamine) 3-O-sulfotransferase 1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; heparan sulfate glucosamine 3-O-sulfotransferase 1; heparin-glucosamine 3-O-sulfotransferase; HS3ST1

Molecular Weight

Mass (kDA):
35.773 kDA

Genomic Context


Human

Location:	4p15.33
Sequence:	4; NC_000004.12 (11393150..11434398, complement)

Tissue Specificity

Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta.

Subcellular Localizations

Golgi apparatus lumen.

Diseases

Blood Coagulation Disorders
Fetal Growth Retardation
Growth Retardation
Infective Disorder
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Hypoxia
Nematode Infections
Carotid Artery Injuries
Neoplasms, Hormone-dependent
Malignant Neoplasms

Neoplasms
Thrombosis
Lupus Erythematosus, Systemic
Mammary Neoplasms
Arterial Injury
Trematode Infections

Pathways

Coagulation
Hemostasis
Blood Coagulation
Sulfation
Reverse Transcription
Glycosylation

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HS3ST1

References

PMID: 9346953 by Shworak N.W., et al. Molecular cloning and expression of mouse and human cDNAs encoding heparan sulfate D-glucosaminyl 3-O-sulfotransferase.

PMID: 8900198 by Liu J., et al. Purification of heparan sulfate D-glucosaminyl 3-O- sulfotransferase.