HS3ST3B1 Antibodies

AND HS3ST3B1 ELISA kits, HS3ST3B1 Proteins

Many biological assays use antibodies to detect HS3ST3B1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HS3ST3B1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HS3ST3B1 antibodies...

We validate the specificity of these antibodies to HS3ST3B1 by testing them on tissues known to express HS3ST3B1 positively and negatively. Browse below to find the HS3ST3B1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HS3ST3B1 Infographic by Boster Bio

All HS3ST3B1 Products

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Specificity

Applications

Price

HS3ST3B1 (NM_006041) Human Over-expression Lysate

Human

$628
Cat # LS009953
100 µg

HS3ST3B1 Overview

Facts about Heparan sulfate glucosamine 3-O-sulfotransferase 3B1.

HS3ST3B1 3D structure. Source: alphafold

Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (HS3ST3B1)

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group into an N- unsubstituted glucosamine connected to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2.

The substrate-specific O-sulfation creates an enzyme-modified heparan sulfate which acts as a binding receptor into Herpes simplex virus-1 (HSV-1) and allows its entrance. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate.

Gene Information

Human
Gene Name:	HS3ST3B1
Uniprot:	Q9Y662
Entrez:	9953

Family

Belongs to:

sulfotransferase 1 family

Alternative Names

3OST3B1; h3-OST-3B; heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1; Heparan Sulfate Glucosamine 3OSulfotransferase 3; HS3ST3B1

Molecular Weight

Mass (kDA):
43.324 kDA

Genomic Context


Human

Location:	17p12
Sequence:	17; NC_000017.11 (14301081..14349406)

Tissue Specificity

Ubiquitous. Most abundant in liver and placenta, followed by heart and kidney.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Hepatitis B
Hepatitis
Virus Diseases
Hiv Infections
Liver Diseases
Acquired Immunodeficiency Syndrome
Dyslipidemias
Dihydropyrimidinase Deficiency
Malaria, Falciparum
Pregnancy Complications, Infectious
Carcinogenesis
Carcinoma

Immunologic Deficiency Syndromes
Misalignment
Malaria
Simian B Disease
Parasitemia
Inherited Neuropathy
Charcot-marie-tooth Disease

Pathways

Gene Silencing
Male Meiosis
Meiosis

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HS3ST3B1

References

PMID: 9988767 by Shworak N.W., et al. Multiple isoforms of heparan sulfate D-glucosaminyl 3-O- sulfotransferase. Isolation, characterization, and expression of human cDNAs and identification of distinct genomic loci.

PMID: 10520990 by Shukla D., et al. A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry.