LIME1 Antibodies

Lck-interacting transmembrane adapter 1 (LIME1)

Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation.

Couples stimulation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules. .

Gene Information

Human
Gene Name:	LIME1
Uniprot:	Q9H400
Entrez:	54923

Family

Belongs to:
No superfamily

Alternative Names

dJ583P15.4; FLJ20406; Lck interacting transmembrane adaptor 1; Lck-interacting membrane protein; Lck-interacting molecule; lck-interacting transmembrane adapter 1; LIMELP8067

Molecular Weight

Mass (kDA):
31.288 kDA

Genomic Context

Human
Location:	20q13.33
Sequence:	20; NC_000020.11 (63735701..63739107)

Tissue Specificity

Expressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level).

Subcellular Localizations

Cell membrane; Single-pass type III membrane protein. Present in lipid rafts. Recruited to the immunological synapse upon conjugation of T-cell with antigen-presenting cell.

PTMs

• Lipoprotein

• Palmitate

• Phosphoprotein

Research Areas

• Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LIME1

Boster Bio - Best Uses Of The LIME1 Marker

Picoband by Boster Bio is a Picokine ELISA platform that you may have heard of. Have you ever wondered about the LIME1 marker and how it works? If so, read on to discover more about this marker. This tool is great for many purposes, including diagnostics and research.

Boster Bio's Picokine ELISA-platform

The Picokine(tm) ELISA platform combines enhanced sensitivity with high specificity and sensitivity, achieving picogram level sensitivity. Picokine(tm), ELISA kit validations can be requested for a wide range of samples. Validation images, procedures and procedures can also be requested. Picoband, a polymer-based secondary antigen, saves IHC researchers at least 30 minutes per sample. The Picoband is powered by insights into immunogen design and is supported by the expertise of BeNeLux distributor Sanbio.

The Picokine(tm) ELISA kits are specifically designed to minimize background, thereby resulting in single-digit picogram level sensitivity. They are tested at 37C for one week, contain enough reagents to run 96 tests and have been validated against many samples. Sanbio and Tebu Bio offer Picokine(tm), ELISA kits for purchase.

Picoband by Boster Bio

Picokine(tm), a high sensitivity ELISA instrument, enhances sensitivity down to the picogram level. It also provides a unique platform for assessing LIME1 gene expression. Picokine (tm) ELISA kits can be validated for multiple samples. They are also available upon request. The Supervision secondary antibody eliminates the need for a second immunohistochemical (IHC) step and saves up to 30 minutes per sample. These innovations are possible because of the insight into immunogen design. Technical support from Sanbio, BeNeLux distributor, is also available.

Picoband LIME1 EISAs are highly sensitive due to the Boster primary antibodies. These antibodies have been validated for use in ELISA, immunohistochemistry, and Western Blotting, and have high affinity. Boster has a large selection of antibodies to match the LIME1 marker.

Boster Bio's LIME1Marker

Boster Bio's anti LIME1 Purified Monoclonal antibody is the best choice if you are interested in conducting experiments on a variety species and applications. The antibody is designed to react with humans and is stored at 2-8degC. It is conjugated to keyhole hemocyanin. Pricing for blocking peptides is dependent on the length of each immunogen. In general, however, blocking peptides cost about $1 - $5 per g.