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LRPPRC Antibodies
AND LRPPRC ELISA kits, LRPPRC Proteins
Many biological assays use antibodies to detect LRPPRC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRPPRC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRPPRC antibodies...
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LRPPRC Infographic by Boster Bio
All LRPPRC Products
Product
Figures
Specificity
Applications
Price
Anti-LRPPRC/GP130 Antibody Picoband®
2 Citations
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03264
100 μg/vial
Cat # A03264
100 μg/vial
LRPPRC Overview
Facts about Leucine-rich PPR motif-containing protein, mitochondrial.
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC)
May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes in late stages of mRNA maturation which are possibly associated with nuclear mRNA export.
May bind mature mRNA from the nucleus outer membrane. In mitochondria binds to poly(A) mRNA.
Gene Information
| Human | |
|---|---|
| Gene Name: | LRPPRC |
| Uniprot: | P42704 |
| Entrez: | 10128 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CLONE-23970; leucine-rich PPR-motif containing; mitochondrial leucine-rich PPR motif-containing protein; mitochondrial
Molecular Weight
Mass (kDA):
157.905 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p21 |
| Sequence: | 2; NC_000002.12 (43886224..43995989, complement) |
Tissue Specificity
Expressed ubiquitously. Expression is highest in heart, skeletal muscle, kidney and liver, intermediate in brain, non-mucosal colon, spleen and placenta, and lowest in small intestine, thymus, lung and peripheral blood leukocytes.
Subcellular Localizations
Mitochondrion. Nucleus, nucleoplasm. Nucleus inner membrane. Nucleus outer membrane. Seems to be predominantly mitochondrial.
Diseases
- Leigh Disease
- Cytochrome-c Oxidase Deficiency
- Peste Des Petits Ruminants Infection
- Neoplasms
- Neurodegenerative Disorders
- Malignant Neoplasms
- Liver Neoplasms
- Liver Carcinoma
- Leukemia
- Mitochondrial Diseases
- Acidosis
- Acidosis, Lactic
- Hepatoblastoma
Interacting Proteins
- APP
- EIF4E
- PPARGC1A
- SLIRP
Pathways
- Translation
- Cell Death
- Localization
- Transport
- Mitochondrial Translation
- Rna Interference
- Oxidative Phosphorylation
- Cell Cycle
- Energy Homeostasis
- Pathogenesis
- Autophagy
- Ras Protein Signal Transduction
- Cellular Homeostasis
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRPPRC
bosterbio.com/bosterbio-gene-info-cards/LRPPRC
References
PMID: 15139850 by Xu F., et al. The role of the LRPPRC (leucine-rich pentatricopeptide repeat cassette) gene in cytochrome oxidase assembly: mutation causes lowered levels of COX (cytochrome c oxidase) I and COX III mRNA.
PMID: 8012652 by Hou J., et al. Molecular cloning and expression of the gene for a major leucine-rich protein from human hepatoblastoma cells (HepG2).
2 Publications of Boster LRPPRC Antibodies & ELISA Kits
- PubMed ID: 10.1007/s10571-021-01052-z, Proteomic Profiling of Cerebrum Mitochondria, Myelin Sheath, and Synaptosome Rev...
- PubMed ID: 33560469, Shen L,Yang A,Chen X,Xiao S,Liu X,Lin J,Zhao Y,Zhang K,Li C,Ke J,Zhang H,Khan NU...
*More publications can be found for each product on its corresponding product page