PLAU Antibodies

Urokinase-type plasminogen activator (PLAU)

Especially cleaves the zymogen plasminogen to form the active enzyme plasmin. .

Gene Information

Human
Gene Name:	PLAU
Uniprot:	P00749
Entrez:	5328

Family

Belongs to:
peptidase S1 family

Alternative Names

ATF; EC 3.4.21; EC 3.4.21.73; plasminogen activator, urokinase; PLAU; uPA; u-PA; uPlasminogen Activator; u-Plasminogen Activator; urinary; Urokinase; urokinase-type plasminogen activator

Molecular Weight

Mass (kDA):
48.507 kDA

Genomic Context

Human
Location:	10q22.2
Sequence:	10; NC_000010.11 (73909182..73917497)

Tissue Specificity

Expressed in the prostate gland and prostate cancers.

Subcellular Localizations

Secreted.

Diseases

• Malignant Neoplasms
• Neoplasms
• Cell Invasion
• Carcinoma
• Neoplasm Metastasis
• Tissue Adhesions
• Alzheimer's Disease
• Malignant Neoplasm Of Breast
• Mammary Neoplasms
• Malignant Squamous Cell Neoplasm
• Malignant Neoplasm Of Prostate
• Inflammation
• Adenocarcinoma

• Prostatic Neoplasms
• Hemorrhage
• Tumor Angiogenesis
• Malignant Neoplasm Of Lung
• Neoplasm Invasiveness
• Cell Transformation, Neoplastic
• Ductal Breast Carcinoma

Pathways

• Pathogenesis
• Cell Adhesion
• Fibrinolysis
• Methylation
• Angiogenesis
• Cell Migration
• Cell Proliferation
• Dna Methylation
• Regeneration
• Transport
• Immune Response
• Cell Cycle
• Wound Healing

• Localization
• Tissue Remodeling
• Cell Growth
• Cell Motility
• Ovulation
• Proteolysis
• Chemotaxis

PTMs

• Methylation
• Phosphorylation
• Demethylation

• Reduction
• Cleavage
• Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLAU

Epigenomics - The Best Uses Of The PLAU Marker

Epigen is a highly-specialized field. It has experienced significant growth in recent years. Understanding how this gene works is vital. This article will go over the fundamentals of this gene as well as its family members: Aldehyde dehydrogenase A3, A2 and B. Below are some of the most intriguing uses of this gene in the field of biology. These may seem complicated, but they aren't.

Epigen

The Boster Bio website offers comprehensive technical information as well as blogs and information about diseases. The Plau marker is a flexible and effective instrument for DNA characterization as well as genetic analysis. Boster Bio has verified the appropriate assays for a variety of types of samples. In addition the company's lysis buffers are of the highest quality which ensures high sensitivity as well as low cross-linking intensities.

Boster Bio is a specialist antibody manufacturer that focuses on high-sensitivity and specific antibodies. Panels of tissues are utilized to validate their products. They are also tested against known amounts of recombinant proteins and untransfected cell lines. They offer a wide range of high-performance ELISA kit and antibodies. There are more than 12,000 available antibodies. Boster Bio validates its antibodies with a variety of platforms, including flow cytometry(FC), WB ELISA and WB.

Aldehyde dehydrogenase 1 family member A3

ALDH2A3 is a possible androgen-responsive gene found in the prostate cancer in humans. It is active in the cellular version of retinoic acids. It is not intended to be used in diagnostic procedures or for the resale of it. It is essential to the human embryo's development. Boster Bio has been producing ALDH2A3 assays and antibodies for more than 15 years.

The HLD enzymes that are present in humans and other animals are identified by diverse sequences. The HLD gene family comprises members with Lys-1 through, Glu-18 and Glu-24, HLDBV65 784582 , HLDBT71 760347 , and HLDGM12 678424. Below are the amino acid sequences of these enzymes.