PLCB2 Antibodies

AND PLCB2 ELISA kits, PLCB2 Proteins

Many biological assays use antibodies to detect PLCB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLCB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLCB2 antibodies...

We validate the specificity of these antibodies to PLCB2 by testing them on tissues known to express PLCB2 positively and negatively. Browse below to find the PLCB2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLCB2 Infographic by Boster Bio

All PLCB2 Products

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Specificity

Applications

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Anti-PLC Beta 2 PLCB2 Antibody

Western blot (WB) analysis of PLC β2 polyclonal antibody at 1:500 dilution
Lane1:Hela cell lysate
Lane2:sp2/0 cell lysate
Lane3:H9C2 cell lysate

Human, Mouse, Rat

$405
Cat # A05927
100ul

Anti-PLC Beta 2 PLCB2 Antibody

Western blot analysis of extracts of Rat lung, using PLCB2 antibody at 1:1000 dilution

Western blot analysis of extracts of HEL cells, using PLCB2 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A05927-1
100ul

Phospholipase C beta 2 (PLCB2) (NM_004573) Human Over-expression Lysate

Human

$960
Cat # LS005330
20 µg, 100 µg

Anti-PLCB2 Antibody Picoband®

Western blot analysis of PLCB2 using anti-PLCB2 antibody (A05927-2)

Flow Cytometry analysis of THP-1 cells using anti-PLCB2 antibody (A05927-2)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A05927-2
100 μg/vial

PLCB2 Overview

Facts about 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2.

PLCB2 3D structure. Source: alphafold

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (PLCB2)

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. .

Gene Information

Human
Gene Name:	PLCB2
Uniprot:	Q00722
Entrez:	5330

Family

Belongs to:

No superfamily

Alternative Names

EC 3.1.4.11; FLJ38135; Phosphoinositide phospholipase C-beta-2,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; phospholipase C, beta 2; Phospholipase C-beta-2; PLC-beta-2

Molecular Weight

Mass (kDA):
134.024 kDA

Genomic Context


Human

Location:	15q15.1
Sequence:	15; NC_000015.10 (40285496..40307945, complement)

Diseases

Pertussis
Tissue Adhesions
Leukemia
Neoplasms
Inflammation
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Carcinoma
Malignant Neoplasms
Acute Promyelocytic Leukemia
Mammary Neoplasms
Chimera Disorder
Ischemia

Malignant Paraganglionic Neoplasm
Peritonitis
Cell Invasion
Cell Transformation, Neoplastic
Pulmonary Thromboembolism
Pulmonary Embolism
Hypoxia

Interacting Proteins

CTNNAL1

Pathways

Localization
Secretion
Chemotaxis
Cell Adhesion
Taste Perception
Platelet Aggregation
Translation
Cell Proliferation
Cell Migration
Neutrophil Differentiation
Platelet Activation
Hypersensitivity
Vasculogenesis

Spermatogenesis
Cell Maturation
Cell Division
Phagocytosis
Cell Cycle
Store-operated Calcium Entry
Exocytosis

PTMs

Phosphorylation

Research Areas

Lipid and Metabolism
Wnt Signaling Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLCB2

References

PMID: 1644792 by Park D., et al. Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2.

PMID: 23625927 by Sun Z., et al. WDR26 functions as a scaffolding protein to promote Gbetagamma- mediated phospholipase C beta2 (PLCbeta2) activation in leukocytes.