CASQ2 Calsequestrin-2 Dog protein

Calsequestrin 2 protein, Rat

Calsequestrin is the major calcium storage protein of the sarcoplasmic reticulum. Intraluminar Ca2+ binds to calsequestrin during diastole to prevent Ca2+ precipitation and to lower its free ionic concentration to facilitate efficient storage. During systole, Calsequestrin coordinately releases ~40-­50 Ca2+ ions per molecule for each contraction-relaxation cycle by an uncertain mechanism. Calsequestrin has been shown to be of major importance in the regulation of cardiac excitation-contraction coupling.

Product Info Summary

SKU: PROTP12637
Size: 2ug, 5ug, 10ug
Origin Species: Rat
Source: Dog heart

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Product Name

CASQ2 Calsequestrin-2 Dog protein

View all Calsequestrin 2 recombinant proteins

SKU/Catalog Number

PROTP12637

Size

2ug, 5ug, 10ug

Description

Calsequestrin is the major calcium storage protein of the sarcoplasmic reticulum. Intraluminar Ca2+ binds to calsequestrin during diastole to prevent Ca2+ precipitation and to lower its free ionic concentration to facilitate efficient storage. During systole, Calsequestrin coordinately releases ~40-­50 Ca2+ ions per molecule for each contraction-relaxation cycle by an uncertain mechanism. Calsequestrin has been shown to be of major importance in the regulation of cardiac excitation-contraction coupling.

Storage & Handling

Lyophilized CASQ2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CASQ2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Cite This Product

CASQ2 Calsequestrin-2 Dog protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP12637)

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

The protein was lyophilized from a concentrated solution (1mg/ml) containing 10mM Tris-HCl and 1mM EGTA.

Purity

Greater than 90% as determined by SDS-PAGE.

Predicted MW

46.436kDa

Reconstitution

It is recommended to reconstitute the lyophilized CASQ2 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

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Reconstitution

It is recommended to reconstitute the lyophilized CASQ2 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Validation Images & Assay Conditions

Gene/Protein Information For CASQ2 (Source: Uniprot.org, NCBI)

Gene Name

CASQ2

Full Name

Calsequestrin-2

Weight

46.436kDa

Superfamily

calsequestrin family

Alternative Names

calsequestrin 2 (cardiac muscle); calsequestrin 2, fast-twitch, cardiac muscle; Calsequestrin, cardiac muscle isoform; calsequestrin-2; FLJ26321; FLJ93514; PDIB2 CASQ2 PDIB2 calsequestrin 2 calsequestrin-2|calsequestrin 2 (cardiac muscle)|calsequestrin 2, fast-twitch, cardiac muscle

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

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Size

Total: $375

SKU:PROTP12637

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