Product Info Summary
SKU: | PROTP12637 |
---|---|
Size: | 2ug, 5ug, 10ug |
Origin Species: | Rat |
Source: | Dog heart |
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Product info
Product Name
CASQ2 Calsequestrin-2 Dog protein
View all Calsequestrin 2 recombinant proteins
SKU/Catalog Number
PROTP12637
Size
2ug, 5ug, 10ug
Description
Calsequestrin is the major calcium storage protein of the sarcoplasmic reticulum. Intraluminar Ca2+ binds to calsequestrin during diastole to prevent Ca2+ precipitation and to lower its free ionic concentration to facilitate efficient storage. During systole, Calsequestrin coordinately releases ~40-50 Ca2+ ions per molecule for each contraction-relaxation cycle by an uncertain mechanism. Calsequestrin has been shown to be of major importance in the regulation of cardiac excitation-contraction coupling.
Storage & Handling
Lyophilized CASQ2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CASQ2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Cite This Product
CASQ2 Calsequestrin-2 Dog protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP12637)
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
The protein was lyophilized from a concentrated solution (1mg/ml) containing 10mM Tris-HCl and 1mM EGTA.
Purity
Greater than 90% as determined by SDS-PAGE.
Predicted MW
46.436kDa
Reconstitution
It is recommended to reconstitute the lyophilized CASQ2 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
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Assay dilution & Images
Reconstitution
It is recommended to reconstitute the lyophilized CASQ2 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Validation Images & Assay Conditions
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Recombinant protein fun image
Protein Target Info & Infographic
Gene/Protein Information For CASQ2 (Source: Uniprot.org, NCBI)
Gene Name
CASQ2
Full Name
Calsequestrin-2
Weight
46.436kDa
Superfamily
calsequestrin family
Alternative Names
calsequestrin 2 (cardiac muscle); calsequestrin 2, fast-twitch, cardiac muscle; Calsequestrin, cardiac muscle isoform; calsequestrin-2; FLJ26321; FLJ93514; PDIB2 CASQ2 PDIB2 calsequestrin 2 calsequestrin-2|calsequestrin 2 (cardiac muscle)|calsequestrin 2, fast-twitch, cardiac muscle
*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".For more info on CASQ2, check out the CASQ2 Infographic
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In this infographic, you will see the following information for CASQ2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].
Specific Publications For CASQ2 Calsequestrin-2 Dog protein (PROTP12637)
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