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Product Info Summary
| SKU: | A07505 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-ACh beta CHRNB1 Antibody
View all Nicotinic Acetylcholine Receptor beta Antibodies
SKU/Catalog Number
A07505
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ACh beta CHRNB1 Antibody catalog # A07505. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ACh beta CHRNB1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07505)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human AChRbeta1
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07505 is reactive to CHRNB1 in Human, Mouse, Rat
Applications
A07505 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
56.698kDa
Background of Nicotinic Acetylcholine Receptor beta
Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A.
Nakajima D., DNA Res. 9:99-106(2002).
Olsen J.V., Cell 127:635-648(2006).
Hirosawa M., DNA Res. 6:329-336(1999).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
ELISA 1:5000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-ACh beta CHRNB1 Antibody A07505
Western Blot (WB) analysis of HeLa cells using AChRbeta1 polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For CHRNB1 (Source: Uniprot.org, NCBI)
Gene Name
CHRNB1
Full Name
Acetylcholine receptor subunit beta
Weight
56.698kDa
Superfamily
ligand-gated ion channel (TC 1.A.9) family
Alternative Names
acetylcholine receptor subunit beta; ACHRB; ACHRBSCCMS; cholinergic receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); CHRNB; CHRNB1; CMS1D; CMS2A; CMS2C; FLJ57107; nAChRB1; Nicotinic Acetylcholine R beta 1 CHRNB1 ACHRB, CHRNB, CMS1D, CMS2A, CMS2C, SCCMS cholinergic receptor nicotinic beta 1 subunit acetylcholine receptor subunit beta|acetylcholine receptor, nicotinic, beta 1 (muscle)|cholinergic receptor, nicotinic beta 1|cholinergic receptor, nicotinic, beta 1 (muscle)|cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CHRNB1, check out the CHRNB1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CHRNB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ACh beta CHRNB1 Antibody (A07505)
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No publications found for A07505
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