Anti-ApoOL/Apolipoprotein O Like Antibody

Product Name

Anti-ApoOL/Apolipoprotein O Like Antibody

View all Apool Antibodies

SKU/Catalog Number

A12075

Size

100μl

Form

Liquid

Description

Boster Bio Anti-ApoOL/Apolipoprotein O Like Antibody catalog # A12075. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ApoOL/Apolipoprotein O Like Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12075)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

F7E4

Isotype

IgG

Immunogen

Synthesized peptide derived from the C-terminal region of human ApoOL. at AA rangle: 190-270

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12075 is reactive to Apool in Human, Mouse, Rat

Applications

A12075 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

29.261kDa

Background of Apool

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of SH-SY5Y 293T 3T3 lysis using ApoOL antibody.

Gene/Protein Information For Apool (Source: Uniprot.org, NCBI)

Alternative Names

AAIR8193; apolipoprotein O-like; chromosome X open reading frame 33; CXorf33; FAM121A; family with sequence similarity 121A; MGC129748; Protein FAM121A; UNQ8193

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In this infographic, you will see the following information for Apool: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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