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Product Info Summary
| SKU: | A03862-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, IHC |
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Product info
Product Name
Anti-ATRIP (D64) Antibody
SKU/Catalog Number
A03862-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ATRIP (D64) Antibody catalog # A03862-1. Tested in IHC,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ATRIP (D64) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03862-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human CRSP130
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03862-1 is reactive to ATRIP in Human, Mouse, Rat
Applications
A03862-1 is guaranteed for IF, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
85.838kDa
Background of ATRIP
Required for transcriptional activation subsequent to the assembly of the preinitiation complex By similarity. Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling.
Wiemann S., Genome Res. 11:422-435(2001).
Mungall A.J., Nature 425:805-811(2003).
Akoulitchev S., Nature 407:102-106(2000).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
IF: 1:50-1:200
Validation Images & Assay Conditions
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Figure 1. Immunohistochemistry validation of ATRIP using Anti-ATRIP (D64) Antibody (A03862-1).
Immunohistochemistry (IHC) analyzes of ATRIP (D64) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For ATRIP (Source: Uniprot.org, NCBI)
Gene Name
ATRIP
Full Name
ATR-interacting protein
Weight
85.838kDa
Superfamily
ATRIP family
Alternative Names
AGS1; ATM and Rad3-related-interacting protein; ATR interacting protein; ATR-interacting protein; ATRIP; DKFZp762J2115; FLJ12343; MGC20625; MGC21482; MGC26740; TREX1 ATRIP ATR interacting protein ATR-interacting protein|ATM and Rad3-related-interacting protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ATRIP, check out the ATRIP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ATRIP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ATRIP (D64) Antibody (A03862-1)
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No publications found for A03862-1
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