Product Info Summary
SKU: | A01821-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IHC |
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Product info
Product Name
Anti-Bile salt-activated lipase CEL Antibody
View all Carboxyl Ester Lipase/CEL Antibodies
SKU/Catalog Number
A01821-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Bile salt-activated lipase CEL Antibody catalog # A01821-1. Tested in ELISA, IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Bile salt-activated lipase CEL Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01821-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human CEL.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01821-1 is reactive to CEL in Human
Applications
A01821-1 is guaranteed for ELISA, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
79.322kDa
Background of Carboxyl Ester Lipase/CEL
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions. Can edit both viral and cellular RNAs and can edit RNAs at multiple sites (hyper-editing) or at specific sites (site-specific editing). Its cellular RNA substrates include: bladder cancer-associated protein (BLCAP), neurotransmitter receptors for glutamate (GRIA2 and GRIK2) and serotonin (HTR2C), GABA receptor (GABRA3) and potassium voltage-gated channel (KCNA1). Site-specific RNA editing of transcripts encoding these proteins results in amino acid substitutions which consequently alter their functional activities. Edits GRIA2 at both the Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently. Can exert a proviral effect towards human immunodeficiency virus type 1 (HIV-1) and enhances its replication via both an editing-dependent and editing-independent mechanism. The former involves editing of adenosines in the 5'UTR while the latter occurs via suppression of EIF2AK2/PKR activation and function. Can inhibit cell proliferation and migration and can stimulate exocytosis.
Mittaz L., Genomics 41:210-217(1997).
Lai F., Mol. Cell. Biol. 17:2413-2424(1997).
Villard L., Somat. Cell Mol. Genet. 23:135-145(1997).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
ELISA 1:40000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For CEL (Source: Uniprot.org, NCBI)
Gene Name
CEL
Full Name
Bile salt-activated lipase
Weight
79.322kDa
Superfamily
type-B carboxylesterase/lipase family
Alternative Names
BAL; bile salt-activated lipase; Bile salt-stimulated lipase; BSDL; BSSL; BSSLbile salt-dependent lipase, oncofetal isoform; bucelipase; carboxyl ester hydrolase; carboxyl ester lipase (bile salt-stimulated lipase); Carboxyl Ester Lipase; CEase; CEL; CELL; Cholesterol esterase; EC 3.1.1; EC 3.1.1.13; EC 3.1.1.3; FAP; FAPP; fetoacinar pancreatic protein; LIPA; lysophospholipase, pancreatic; MODY8bile-salt-activated lipase; Pancreatic lysophospholipase; Sterol esterase CEL BAL, BSDL, BSSLL, CEase, FAP, FAPP, LIPA, MODY8, CEL carboxyl ester lipase bile salt-activated lipase|bucelipase|carboxyl ester hydrolase|carboxyl ester lipase (bile salt-stimulated lipase)|cholesterol esterase|fetoacinar pancreatic protein|lysophospholipase, pancreatic|sterol esterase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CEL, check out the CEL Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CEL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Bile salt-activated lipase CEL Antibody (A01821-1)
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No publications found for A01821-1
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