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Product Info Summary
| SKU: | A05577 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IHC-P |
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Product info
Product Name
Anti-BOK Antibody
SKU/Catalog Number
A05577
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-BOK Antibody (Catalog # A05577). Tested in ELISA, IHC-P applications. This antibody reacts with Human.
Storage & Handling
BOK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-BOK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05577)
Host
Rabbit
Contents
BOK Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK. The immunogen is located within the first 50 amino acids of BOK.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of BOK are known to exist; this antibody will not detect the smallest isoform. BOK antibody is predicted to not cross-react with other Bcl-2 protein family members
Reactive Species
A05577 is reactive to BOK in Human
Applications
A05577 is guaranteed for ELISA, IHC-P Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
23.28kDa
Background of BOK
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
BOK antibody can be used for detection of BOK by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Immunohistochemistry of BOK in human brain tissue with BOK antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For BOK (Source: Uniprot.org, NCBI)
Gene Name
BOK
Full Name
Bcl-2-related ovarian killer protein
Weight
23.28kDa
Superfamily
Bcl-2 family
Alternative Names
bcl2-L-9; BCL2L9bcl-2-related ovarian killer protein; Bcl-2-like protein 9; BCL2-related ovarian killer; BOK; BOKL; hBOK; MGC4631 BOK BCL2L9L, BOK BCL2 family apoptosis regulator BOK bcl-2-related ovarian killer protein|BCL2 related ovarian killer|BOK, BCL2 family apoptosis regulator|bcl-2-like protein 9|bcl2-L-9|hBOK
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BOK, check out the BOK Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BOK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-BOK Antibody (A05577)
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No publications found for A05577
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Recommended Resources
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Customer Reviews
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