Product Info Summary
SKU: | A01095-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-C4 Antibody
SKU/Catalog Number
A01095-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-C4 Antibody catalog # A01095-2. Tested in WB,ICC/IF,IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-C4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01095-2)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human C4A, which shares 86.8% and 87.2% amino acid (aa) sequence identity with mouse and rat C4A, respectively.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01095-2 is reactive to C4A in Human
Applications
A01095-2 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
192.785kDa
Background of C4A
Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation.
Gluck SL, et al. (2004) J Clin Invest; 114(12): 1696-1699
Benzing T, et al. (2001) Proc Natl Acad Sci U S A; 98(17): 9784-9789
Tian D, et al. (2002) Mol Cell Biol; 22(8): 2650-2662
Lu Z, et al. (2001) Mol Cell Biol; 21(12): 4016-4031
Krishnan HH, et al. (2006) J Virol; 80(3): 1167-1180
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:200-1:500
ICC: 1:50-1:200
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunocytochemistry staining of C4A using Anti-C4 Antibody (A01095-2).
ICC staining C4 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehydeClick image to see more details
Figure 1. Western blotting validation for Anti-C4 Antibody A01095-2
Western blot analysis of C4 on human liver tissue lysate using anti-C4 antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For C4A (Source: Uniprot.org, NCBI)
Gene Name
C4A
Full Name
Complement C4-A
Weight
192.785kDa
Alternative Names
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C4; complement component 4A (Rodgers blood group); RG C4A C42, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, C4A complement C4A (Rodgers blood group) complement C4-A|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2|C4A anaphylatoxin|MHC class III region complement|Rodgers form of C4|acidic C4|acidic complement C4|complement component 4A (Rodgers blood group)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on C4A, check out the C4A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for C4A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-C4 Antibody (A01095-2)
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No publications found for A01095-2
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Customer Reviews
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