Anti-Caspase-5 CASP5 Antibody

Caspase 5 antibody

Boster Bio Anti-Caspase-5 CASP5 Antibody (Catalog # A05259-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A05259-1
Size: 0.1 mg
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, IF, ICC, WB

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Product Name

Anti-Caspase-5 CASP5 Antibody

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SKU/Catalog Number



0.1 mg




Boster Bio Anti-Caspase-5 CASP5 Antibody (Catalog # A05259-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

Caspase-5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Caspase-5 CASP5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05259-1)




Caspase-5 Antibody is supplied in PBS containing 0.02% sodium azide.






Caspase-5 antibody was raised against a 14 amino acid synthetic peptide from the center of human Caspase-5. The immunogen is located within amino acids 170 - 220 of Caspase-5.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.


Depending on cell lines or tissues used, other cleavage products may be observed.

Reactive Species

A05259-1 is reactive to CASP5 in Human, Mouse


A05259-1 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Background of Caspase 5

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1β and IL-18. Caspase-5 can interact with caspase-1; both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1β. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Casp-5 antibody can be used for the detection of caspase-5 by Western blot at 0.5 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 2 μg/mL. Antibody validated: Western Blot in human samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Validation Images & Assay Conditions

Gene/Protein Information For CASP5 (Source:, NCBI)

Uniprot ID


Gene ID


Gene Name


Full Name





peptidase C14A family

Alternative Names

CASP5; CASP-5; caspase 5, apoptosis-related cysteine peptidase; caspase 5, apoptosis-related cysteine protease; Caspase5; Caspase-5; EC 3.4.22; EC; ICE(rel)III; ICE(rel)-III; ICEREL-III; ICH3; ICH-3; MGC141966; Protease ICH-3; Protease TY; TY protease CASP5 ICE(rel)III, ICEREL-III, ICH-3 caspase 5 caspase-5|TY protease|caspase 5 variant X1|caspase 5, apoptosis-related cysteine peptidase|caspase 5, apoptosis-related cysteine protease|protease ICH-3|protease TY

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CASP5, check out the CASP5 Infographic

CASP5 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CASP5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Ships directly to USA and Canada. For other regions, visit our distributors page

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)



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