Product Info Summary
SKU: | PA1549 |
---|---|
Size: | 100 μg/vial |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-CD89/FCAR Antibody
SKU/Catalog Number
PA1549
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-CD89/FCAR Antibody catalog # PA1549. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CD89/FCAR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1549)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence in the middle of human CD89.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1549 is reactive to FCAR in Human
Applications
PA1549 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
34 kDa
Calculated molecular weight
32.265kDa
Background of FCAR/CD89
FCAR, Receptor for Fc fragment of IGA, is also known as CD89. Human Fc-alpha receptor (FCAR) is present on a number of cell types, including neutrophils, monocytes, macrophages, and eosinophils. FCAR interacts with aggregated IgAs, such as IgA coated on the surface of an invading microorganism, and mediates several immunologic defense processes such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. FCAR is a glycoprotein of 50 to 100 kD, with diversity on different cell types. FCAR is mapped to 19q13.4. Human COS cells transfected with FCAR cDNA bind to IgA, but not IgG.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human
Validation Images & Assay Conditions
Click image to see more details
Anti-CD89 antibody, PA1549, Western blotting
Lane 1: A549 Cell Lysate
Lane 2: U87 Cell Lysate
Lane 3: RAJI Cell Lysate
Lane 4: JURKAT Cell Lysate
Protein Target Info & Infographic
Gene/Protein Information For FCAR (Source: Uniprot.org, NCBI)
Gene Name
FCAR
Full Name
Immunoglobulin alpha Fc receptor
Weight
32.265kDa
Alternative Names
CD89 antigen; CD89; CD89IgA Fc receptor; Fc alpha receptor; Fc fragment of IgA, receptor for; FCAR; immunoglobulin alpha Fc receptor FCAR CD89, CTB-61M7.2, FcalphaRI Fc fragment of IgA receptor immunoglobulin alpha Fc receptor|FCAR variant 14|Fc alpha receptor|Fc fragment of IgA, receptor for
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FCAR, check out the FCAR Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FCAR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CD89/FCAR Antibody (PA1549)
Hello CJ!
No publications found for PA1549
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-CD89/FCAR Antibody
Question
We are currently using anti-CD89/FCAR antibody PA1549 for human tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on dog tissues as well?
A. Singh
Verified customer
Asked: 2014-01-30
Answer
The anti-CD89/FCAR antibody (PA1549) has not been tested for cross reactivity specifically with dog tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2014-01-30