Product Info Summary
SKU: | A06988 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, ICC, WB |
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Product info
Product Name
Anti-CPT1C Antibody
SKU/Catalog Number
A06988
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CPT1C Antibody catalog # A06988. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CPT1C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06988)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
A synthetic peptide corresponding to residues in Human RGMB
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06988 is reactive to Cpt1c in Human, Mouse, Rat
Applications
A06988 is guaranteed for IF, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
90.03kDa
Background of Cpt1c
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Celeste A.J., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 434:724-731(2005).
Mazerbourg S., J. Biol. Chem. 280:32122-32132(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-CPT1C Antibody A06988
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For Cpt1c (Source: Uniprot.org, NCBI)
Gene Name
Cpt1c
Full Name
Carnitine O-palmitoyltransferase 1, brain isoform
Weight
90.03kDa
Superfamily
carnitine/choline acetyltransferase family
Alternative Names
carnitine O-palmitoyltransferase 1, brain isoform; Carnitine O-palmitoyltransferase I, brain isoform; carnitine palmitoyltransferase 1CCPT1-B; carnitine palmitoyltransferase I related C; CATL1; CPT IC; CPT1P; CPTI-B; CPTIC; EC 2.3.1.21; FLJ23809 Cpt1c|6530437J22Rik, 9630004I06Rik, CPT I-C, CPT IC, CPT1-B, CPTI-B|carnitine palmitoyltransferase 1c|carnitine O-palmitoyltransferase 1, brain isoform|carnitine palmitoyltransferase 1, brain
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Cpt1c, check out the Cpt1c Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Cpt1c: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CPT1C Antibody (A06988)
Hello CJ!
No publications found for A06988
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Customer Reviews
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