Product Info Summary
SKU: | A02112 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-CPT2 Antibody
SKU/Catalog Number
A02112
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CPT2 Antibody catalog # A02112. Tested in WB,ICC/IF,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CPT2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02112)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Shb around the phosphorylation site of Y246.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02112 is reactive to CPT2 in Human, Mouse, Rat
Applications
A02112 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
73.777kDa
Background of CPT2
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) By similarity. Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
Hateboer G., EMBO J. 14:3159-3169(1995).
Deloukas P., Nature 429:375-381(2004).
Matsuoka S., Science 316:1160-1166(2007).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1,000
ICC: 1:50-1:200
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunocytochemistry staining of CPT2 using Anti-CPT2 Antibody (A02112).
ICC staining CPT2 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehydeClick image to see more details
Figure 1. Western blotting validation for Anti-CPT2 Antibody A02112
Western blot analysis of CPT2 on different lysates using anti-CPT2 antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For CPT2 (Source: Uniprot.org, NCBI)
Gene Name
CPT2
Full Name
Carnitine O-palmitoyltransferase 2, mitochondrial
Weight
73.777kDa
Superfamily
carnitine/choline acetyltransferase family
Alternative Names
carnitine O-palmitoyltransferase 2, mitochondrial; carnitine palmitoyltransferase 2; Carnitine palmitoyltransferase IIEC 2.3.1.21; CPT II; CPT1; CPTASE CPT2 CPT1, CPTASE, IIAE4 carnitine palmitoyltransferase 2 carnitine O-palmitoyltransferase 2, mitochondrial|CPT II|carnitine palmitoyltransferase II|testicular secretory protein Li 13
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CPT2, check out the CPT2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CPT2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CPT2 Antibody (A02112)
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No publications found for A02112
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