Anti-CSE1L (E2) Antibody

Product Name

Anti-CSE1L (E2) Antibody

View all CSE1L/CAS/Exportin-2 Antibodies

SKU/Catalog Number

A04496-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-CSE1L (E2) Antibody catalog # A04496-1. Tested in WB,IHC,IP,IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CSE1L (E2) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04496-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human FOXD3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04496-1 is reactive to CSE1L in Human, Mouse, Rat

Applications

A04496-1 is guaranteed for IP, IF, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

110.417kDa

Background of CSE1L/CAS/Exportin-2

Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.

Gregory S.G., Nature 441:315-321(2006).
Guo Y., Proc. Natl. Acad. Sci. U.S.A. 99:3663-3667(2002).
Ramsey H.C., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200
IP: 1:50-1:200
IF: 1:50-1:200

Validation Images & Assay Conditions

Click image to see more details

Figure 2. Immunohistochemistry validation of CSE1L using Anti-CSE1L (E2) Antibody (A04496-1).

Immunohistochemistry (IHC) analyzes of CSE1L (E2) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
For more protocol information of IHC

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Figure 1. Western blotting validation for Anti-CSE1L (E2) Antibody A04496-1

Western blot (WB) analysis of CSE1L (E2) polyclonal antibody at 1:500 dilution
Lane1:HepG2 whole cell lysate(40ug)
Lane2:SGC7901 whole cell lysate(40ug)
Lane3:CT26 whole cell lysate(40ug)
Lane4:PC12 whole cell lysate(40ug)
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration

Gene/Protein Information For CSE1L (Source: Uniprot.org, NCBI)

Alternative Names

CAS; CASMGC117283; Cellular apoptosis susceptibility protein; chromosome segregation 1 (yeast homolog)-like; Chromosome segregation 1-like protein; CSE1 chromosome segregation 1-like (yeast); CSE1; CSE1L; exp2; exportin-2; Importin-alpha re-exporter; MGC130037; XPO2; XPO2MGC130036 CSE1L CAS, CSE1, XPO2 chromosome segregation 1 like exportin-2|CSE1 chromosome segregation 1-like|cellular apoptosis susceptibility protein|chromosome segregation 1-like protein|epididymis secretory sperm binding protein|exp2|importin-alpha re-exporter

For more info on CSE1L, check out the CSE1L Infographic

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In this infographic, you will see the following information for CSE1L: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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