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Product Info Summary
| SKU: | A05417-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Cytochrome P450 3A7 CYP3A7 Antibody
SKU/Catalog Number
A05417-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Cytochrome P450 3A7 CYP3A7 Antibody catalog # A05417-1. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cytochrome P450 3A7 CYP3A7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05417-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human Cytochrome P450 3A7.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05417-1 is reactive to CYP3A7 in Human, Mouse, Rat
Applications
A05417-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
57.47kDa
Background of CYP3A7
This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3AP1 pseudogene and is represented by GeneID:100861540.
Komori M., J. Biochem. 105:161-163(1989).
Gellner K., Pharmacogenetics 11:111-121(2001).
Scherer S.W., Science 300:767-772(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-Cytochrome P450 3A7 CYP3A7 Antibody A05417-1
Western blot (WB) analysis of CYP3A7 polyclonal antibody at 1:500 dilutionLane1:HEK293T cell lysate
Lane2:Raw264.7 cell lysate
Lane3:PC12 cell lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For CYP3A7 (Source: Uniprot.org, NCBI)
Gene Name
CYP3A7
Full Name
Cytochrome P450 3A7
Weight
57.47kDa
Superfamily
cytochrome P450 family
Alternative Names
CYPIIIA7; cytochrome P450, family 3, subfamily A, polypeptide 7; Cytochrome P450-HFLA; EC 1.14.14.1; flavoprotein-linked monooxygenase; microsomal monooxygenase; subfamily IIIA, polypeptide 7; xenobiotic monooxygenase CYP3A7 CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA, P450HLp2 cytochrome P450 family 3 subfamily A member 7 cytochrome P450 3A7|aryl hydrocarbon hydroxylase|cytochrome P450, family 3, subfamily A, polypeptide 7|cytochrome P450, subfamily IIIA, polypeptide 7|cytochrome P450-HFLA|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CYP3A7, check out the CYP3A7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CYP3A7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cytochrome P450 3A7 CYP3A7 Antibody (A05417-1)
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No publications found for A05417-1
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