Anti-Embigin, EMB Antibody

Product Name

Anti-Embigin, EMB Antibody

View all Embigin homolog Antibodies

SKU/Catalog Number

A02826

Size

100 µg

Form

Liquid

Description

Boster Bio Anti-Embigin, EMB Antibody (Catalog# A02826). Tested in WB application(s). This antibody reacts with Human.

Storage & Handling

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Cite This Product

Anti-Embigin, EMB Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02826)

Host

Rabbit

Contents

100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A partial length recombinant Embigin, EMB protein (amino acids 100-250)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A02826 is reactive to Emb in Human

Applications

A02826 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

37.064kDa

Background of Embigin homolog

FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is ubiquitously expressed. Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot: 2-4 µg/ml

Validation Images & Assay Conditions

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Western blot analysis of Embigin, EMB. Anti-Embigin, EMB antibody was used at 2 μg/ml on (1) PC3 and (2) Jurkat lysates.

Gene/Protein Information For Emb (Source: Uniprot.org, NCBI)

Alternative Names

EMB; embigin homolog (mouse); embigin homolog; Embigin; F9; GP70; H; MGC71745 Emb|AL022799, Gp7, Gp70|embigin|embigin|glycoprotein 70|teratocarcinoma glycoprotein Gp-70

For more info on Emb, check out the Emb Infographic

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In this infographic, you will see the following information for Emb: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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