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Product Info Summary
| SKU: | A31838 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-ERRF SRARP Antibody
SKU/Catalog Number
A31838
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ERRF SRARP Antibody (Catalog # A31838). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
ERRF antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-ERRF SRARP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A31838)
Host
Rabbit
Contents
ERRF Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
ERRF antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ERRF . The immunogen is located within the last 50 amino acids of ERRF.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
It is predicted to not cross-react with other members of the cavin family.
Reactive Species
A31838 is reactive to SRARP in Human, Mouse
Applications
A31838 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
17.657kDa
Background of SRARP
The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ERRF Antibody can be used for detection of ERRF by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human and mouse samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ERRF in (A) HeLa and (B) A-20 cell lysate with ERRF antibody at 1 μg/mL.
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Immunocytochemistry of ERRF in HeLa cells with ERRF antibody at 2.5 μg/ml.
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Immunofluorescence of ERRF in HeLa cells with ERRF antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For SRARP (Source: Uniprot.org, NCBI)
Gene Name
SRARP
Full Name
Steroid receptor-associated and regulated protein
Weight
17.657kDa
Alternative Names
Steroid receptor-associated and regulated protein SRARP C1orf64, ERRF steroid receptor associated and regulated protein steroid receptor-associated and regulated protein|ER-related factor|steroid receptor-regulated protein|uncharacterized protein C1orf64
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SRARP, check out the SRARP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SRARP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ERRF SRARP Antibody (A31838)
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No publications found for A31838
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Customer Reviews
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