Anti-Fibulin-2 FBLN2 Monoclonal Antibody

Product Name

Anti-Fibulin-2 FBLN2 Monoclonal Antibody

View all Fibulin 2 Antibodies

SKU/Catalog Number

M07304

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Fibulin-2 FBLN2 Monoclonal Antibody catalog # M07304. Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Fibulin-2 FBLN2 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M07304)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

7H4F6/3B9A11

Isotype

IgG

Immunogen

Purified recombinant fragment of Fibulin-2 (aa180-440) expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M07304 is reactive to FBLN2 in Human

Applications

M07304 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

126.573kDa

Background of Fibulin 2

Tissue inhibitor of metalloproteinase-4 (TIMP-4) is member of the TIMP family of inhibitors of matrix metalloproteinase (MMP) activities. In addition, TIMPs have non-MMP associated functions, including roles in growth promotion, apoptosis, and angiogenesis. All four members of the TIMP gene family form a similar secondary structure due to the formation of six highly conserved disulfide bonds. It has been reported that some TIMPs, TIMP4 included, can bind a tetraspanin in the plasma membrane, initiating an intra-cellular signaling cascade. Elevated levels of TIMP4 have been associated with breast cancer progression and heart disease.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
ELISA 1:10000

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-Fibulin-2 FBLN2 Monoclonal Antibody M07304

Western Blot (WB) analysis using Fibulin-2 Monoclonal Antibody against truncated FBLN2-Trx recombinant protein (1) and truncated FBLN2 (aa28-444)-hIgGFc transfected COS7 cell lysate(2).
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration

Gene/Protein Information For FBLN2 (Source: Uniprot.org, NCBI)

Alternative Names

FBLN2; FIBL-2; Fibulin 2; Fibulin-2 FBLN2 fibulin 2 fibulin-2|FIBL-2

For more info on FBLN2, check out the FBLN2 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for FBLN2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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