Anti-H4K5,8,12ac HIST1H4A Antibody

H4C1 antibody

Boster Bio Anti-H4K5,8,12ac HIST1H4A Antibody (Catalog# CI1033). Tested in ChIP, ChIP-seq, ELISA, Dot blot, WB, IF applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: CI1033
Size: 50μg/66μl
Reactive Species: Human, Mouse
Host: Rabbit
Application: ChIP, ChIP-seq, Dot blot, ELISA, IF, WB

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Product Name

Anti-H4K5,8,12ac HIST1H4A Antibody

View all H4C1 Antibodies

SKU/Catalog Number

CI1033

Size

50μg/66μl

Form

Liquid

Description

Boster Bio Anti-H4K5,8,12ac HIST1H4A Antibody (Catalog# CI1033). Tested in ChIP, ChIP-seq, ELISA, Dot blot, WB, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C. For long-term storage, store at -80°C. Avoid multiple freeze-thaw cycles.

Cite This Product

Anti-H4K5,8,12ac HIST1H4A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # CI1033)

Host

Rabbit

Contents

Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.

Clonality

Polyclonal

Immunogen

This antibody is raised in rabbit against the region of histone H4 containing the acetylated lysines 5, 8 and 12 (H4K5,8,12ac), using a KLH-conjugated synthetic peptide.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

CI1033 is reactive to H4C1 in Human, Mouse

Applications

CI1033 is guaranteed for ChIP, ChIP-seq, Dot blot, ELISA, IF, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

11.367kDa

Background of H4C1

Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called “histone code”. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Acetylation of histone H4 is associated with active genes.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

User needs to optimize the dilution ratio for this antibody.

Validation Images & Assay Conditions

Gene/Protein Information For H4C1 (Source: Uniprot.org, NCBI)

Gene Name

H4C1

Full Name

Histone H4

Weight

11.367kDa

Superfamily

histone H4 family

Alternative Names

Histone H4 H4C1 H4-161, H4C12, H4C13, H4C14, H4C15, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4FA, HIST1H4A, H4C1 H4 clustered histone 1 histone H4|H4 histone family, member A|histone 1, H4a|histone cluster 1 H4 family member a|histone cluster 1, H4a

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on H4C1, check out the H4C1 Infographic

H4C1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for H4C1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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CI1033
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$479.00

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