Anti-Human ARSA DyLight® 488 conjugated Antibody(monoclonal, 4C10)

Product Name

Anti-Human ARSA DyLight® 488 conjugated Antibody(monoclonal, 4C10)

View all Arylsulfatase A/ARSA Antibodies

SKU/Catalog Number

M02583-Dyl488

Size

100 μg/vial

Form

Liquid

Description

Boster Bio Anti-Human ARSA DyLight® 488 conjugated Antibody (monoclonal, 4C10) catalog # M02583-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Storage & Handling

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Cite This Product

Anti-Human ARSA DyLight® 488 conjugated Antibody(monoclonal, 4C10) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02583-Dyl488)

Host

Mouse

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Clonality

Monoclonal

Clone Number

4C10

Isotype

Mouse IgG2a

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human ARSA, different from the related mouse sequence by six amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

M02583-Dyl488 is reactive to ARSA in Human

Reconstitution

Observed Molecular Weight

39 kDa

Calculated molecular weight

53.588kDa

Background of Arylsulfatase A/ARSA

Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate intocerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. ARSA is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M02583-Dyl488 is guaranteed for Flow Cytometry Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells

Validation Images & Assay Conditions

Gene/Protein Information For ARSA (Source: Uniprot.org, NCBI)

Alternative Names

Arylsulfatase A; ASA; Cerebroside-sulfatase; Arylsulfatase A component B; Arylsulfatase A component C; ARSA ARSA ASA, MLD arylsulfatase A arylsulfatase A|cerebroside-sulfatase|epididymis secretory sperm binding protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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