Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated

Product Name

Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated

View all CD38 Antibodies

SKU/Catalog Number

FC00193

Size

100ug, 500ug

Form

Liquid

Description

Boster Bio Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated (Catalog# FC00193). Tested in Flow Cytometry application(s). This antibody reacts with Human, Rhesus monkey, Cynomolgus monkey, Baboon.

Storage & Handling

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC00193)

Host

Mouse

Contents

PBS pH 7.2, 0.1% (w/v) BSA, 0.09% (w/v) sodium azide

Clonality

Monoclonal

Clone Number

Clone: OKT10

Isotype

IgG1,k

Immunogen

Human acute lymphoblastic leukaemia cells

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

FC00193 is reactive to CD38 in Cynomolgus monkey, Human, Baboon, Rhesus monkey

Applications

FC00193 is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

34.328kDa

Background of CD38

ITGAM (Integrin Alpha-M), also called CD11B or Mo1 ALPHA SUBUNIT (MO1A), is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (alphaMbeta2) molecule. A major surface antigen family on human leukocytes includes complement receptor type 3 (CR3A; also called ITGAM, Mac1, or Mo1), lymphocyte function-associated (LFA) antigen type 1 (ITGAL), and p150, 95 (ITGAX). By in situ hybridization, Corbi et al. (1988) demonstrated that the genes encoding the alpha subunits of LFA1 (ITGAL), Mac1, and p150, 95 (ITGAX), all of which are involved in leukocyte adhesion, constitute a cluster on 16p13.1-p11. Callen et al. (1991) narrowed the assignment to 16p11.2. Inflammation plays an essential role in the initiation and progression of atherosclerosis. Simon et al. (2000) presented evidence that it also has a role in vascular repair after mechanical arterial injury (i.e., percutaneous transluminal coronary angioplasty, or PTCA).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

User needs to optimize the dilution ratio for this antibody.

Validation Images & Assay Conditions

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Lymphocytes gated PBMCs stained with purified anti-human CD38 (clone OKT-10) followed by Goat anti-mouse IgG (H+L) Alexa Fluor 488 (red histogram). PBMCs monocytes stained with only Goat antimouse IgG (H+L) Alexa Fluor 488 (Blue histogram).

Gene/Protein Information For CD38 (Source: Uniprot.org, NCBI)

Alternative Names

ADP-ribosyl cyclase 1; ADP-ribosyl Cyclase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; cADPr hydrolase 1; CD38 antigen (p45); CD38 antigen; CD38 molecule; CD38; Cyclic ADP-ribose hydrolase 1; Cyclic ADP-ribose Hydrolase; EC 3.2.2.5; NAD(+) nucleosidase; T10 CD38 ADPRC 1, ADPRC1 CD38 molecule ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1|2-phospho-ADP-ribosyl cyclase|2-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|CD38 antigen (p45)|NAD(+) nucleosidase|cluster of differentiation 38|cyclic ADP-ribose hydrolase 1|ecto-nicotinamide adenine dinucleotide glycohydrolase

For more info on CD38, check out the CD38 Infographic

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In this infographic, you will see the following information for CD38: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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