Product Info Summary
SKU: | A08581 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Ik3-1 CABLES1 Antibody
SKU/Catalog Number
A08581
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Ik3-1 CABLES1 Antibody (Catalog # A08581). Tested in WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Ik3-1 CABLES1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08581)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human Ik3-1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A08581 is reactive to Cables1 in Human, Mouse
Applications
A08581 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
61.429kDa
Background of Cables1
Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death By similarity.
Ota T., Nat. Genet. 36:40-45(2004).
Nusbaum C., Nature 437:551-555(2005).
Wu C.-L., Cancer Res. 61:7325-7332(2001).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from LOVO cells, using Ik3-1 antibody A08581.
Protein Target Info & Infographic
Gene/Protein Information For Cables1 (Source: Uniprot.org, NCBI)
Gene Name
Cables1
Full Name
CDK5 and ABL1 enzyme substrate 1
Weight
61.429kDa
Superfamily
cyclin family
Alternative Names
CABL1; CABLES; Cdk5 and Abl enzyme substrate 1; CDK5 and ABL1 enzyme substrate 1; FLJ35924; HsT2563; IK3-1; Interactor with CDK3 1 Cables1|Cables, ik3-, ik3-1|CDK5 and Abl enzyme substrate 1|CDK5 and ABL1 enzyme substrate 1|cdk3-binding protein ik3-1|interactor with CDK3 1|interactor-1 with cdk3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Cables1, check out the Cables1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Cables1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ik3-1 CABLES1 Antibody (A08581)
Hello CJ!
No publications found for A08581
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Customer Reviews
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Customer Q&As
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4 Customer Q&As for Anti-Ik3-1 CABLES1 Antibody
Question
We are currently using anti-Ik3-1 antibody A08581 for mouse tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse. Is it likely that the antibody can work on bovine tissues as well?
C. Gonzalez
Verified customer
Asked: 2018-07-12
Answer
The anti-Ik3-1 antibody (A08581) has not been validated for cross reactivity specifically with bovine tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in bovine you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2018-07-12
Question
We appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for cervix carcinoma using anti-Ik3-1 antibody A08581. Let me know if you need anything else.
Verified Customer
Verified customer
Asked: 2018-05-15
Answer
I appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2018-05-15
Question
Would anti-Ik3-1 antibody A08581 work for WB with cervix carcinoma?
E. Zhang
Verified customer
Asked: 2013-11-13
Answer
According to the expression profile of cervix carcinoma, CABLES1 is highly expressed in cervix carcinoma. So, it is likely that anti-Ik3-1 antibody A08581 will work for WB with cervix carcinoma.
Boster Scientific Support
Answered: 2013-11-13
Question
See attached the WB image, lot number and protocol we used for cervix carcinoma using anti-Ik3-1 antibody A08581. Please let me know if you require anything else.
S. Bhatt
Verified customer
Asked: 2013-10-16
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2013-10-16