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Product Info Summary
| SKU: | A05882 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, IHC, WB |
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Product info
Product Name
Anti-Inositol monophosphatase 1 IMPA1 Antibody
SKU/Catalog Number
A05882
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Inositol monophosphatase 1 IMPA1 Antibody catalog # A05882. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Inositol monophosphatase 1 IMPA1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05882)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human CD164
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05882 is reactive to IMPA1 in Human, Mouse, Rat
Applications
A05882 is guaranteed for IF, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
30.189kDa
Background of IMPA1
Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.
Nagase T., DNA Res. 5:355-364(1998).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC/IF: 1:50-1:200
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For IMPA1 (Source: Uniprot.org, NCBI)
Gene Name
IMPA1
Full Name
Inositol monophosphatase 1
Weight
30.189kDa
Superfamily
inositol monophosphatase superfamily
Alternative Names
EC 3.1.3.25; IMP 1; IMP; IMP1; IMPA; IMPA1; IMPase 1; inositol monophosphatase 1; inositol(myo)-1(or 4)-monophosphatase 1; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; MRT59; Myo-Inositol Monophosphatase 1 IMPA1 IMP, IMPA, MRT59 inositol monophosphatase 1 inositol monophosphatase 1|D-galactose 1-phosphate phosphatase|IMP 1|IMPase 1|inositol(myo)-1(or 4)-monophosphatase 1|inositol-1(or 4)-monophosphatase 1|lithium-sensitive myo-inositol monophosphatase A1|myo-inositol monophosphatase 1|testicular tissue protein Li 94
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IMPA1, check out the IMPA1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IMPA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Inositol monophosphatase 1 IMPA1 Antibody (A05882)
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No publications found for A05882
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