Product Info Summary
SKU: | A07646-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Kallikrein-15 KLK15 Antibody
View all Kallikrein 15 Antibodies
SKU/Catalog Number
A07646-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Kallikrein-15 KLK15 Antibody catalog # A07646-2. Tested in IHC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Kallikrein-15 KLK15 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07646-2)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human KLK15
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07646-2 is reactive to KLK15 in Human
Applications
A07646-2 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
28.087kDa
Background of Kallikrein 15
Component of centriolar satellites, which build a complex and dynamic network required to regulate cilia/flagellum formation. During normal and stress-induced ciliogenesis, its non-ubiquitinated form is rapidly displaced from centriolar satellites and recruited to centrosome/basal bodies in a p38 MAPK-dependent manner. In contrast, in proliferating cells, MIB1-mediated ubiquitination induces its sequestration within centriolar satellites, precluding untimely cilia formation initiation. Acts also as a negative regulator for the trafficking from the centriolar satellite BBSome protein complex to the cilia. Plays a role in sperm flagellar formation; may be involved in the regulation of intraflagellar transport (IFT) and/or intramanchette (IMT) trafficking, which are important for axoneme extension and/or cargo delivery to the nascent sperm tail. Required for optimal cell proliferation and cell cycle progression; may play a role in the regulation of genome stability and centriole duplication in non-ciliogenic cells.
Kikuno R., DNA Res. 6:197-205(1999).
Andersen J.S., Nature 426:570-574(2003).
Olsen J.V., Cell 127:635-648(2006).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC-p 1:50-200, WB 1:500-2000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For KLK15 (Source: Uniprot.org, NCBI)
Gene Name
KLK15
Full Name
Kallikrein-15
Weight
28.087kDa
Superfamily
peptidase S1 family
Alternative Names
ACO protease; ACO; EC 3.4.21; EC 3.4.21.-; EC 3.4.21.4; HSRNASPH; Kallikrein 15; kallikrein-15; kallikrein-like serine protease; kallikrein-related peptidase 15; KLK15; Prostinogen KLK15 ACO, HSRNASPH kallikrein related peptidase 15 kallikrein-15|ACO protease|kallikrein-like serine protease|prostinogen
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KLK15, check out the KLK15 Infographic
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In this infographic, you will see the following information for KLK15: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Kallikrein-15 KLK15 Antibody (A07646-2)
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No publications found for A07646-2
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