Product Info Summary
SKU: | A03287 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, IF, IHC |
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Product info
Product Name
Anti-Laminin alpha-2 LAMA2 Antibody
View all Laminin alpha 2 Antibodies
SKU/Catalog Number
A03287
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Laminin alpha-2 LAMA2 Antibody catalog # A03287. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Laminin alpha-2 LAMA2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03287)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Laminin alpha-2
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03287 is reactive to LAMA2 in Human, Mouse
Applications
A03287 is guaranteed for ELISA, IF, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
343.905kDa
Background of Laminin alpha 2
Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation By similarity. Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.
Enomoto A., Dev. Cell 9:389-402(2005).
Simpson F., Traffic 6:442-458(2005).
Hillier L.W., Nature 434:724-731(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For LAMA2 (Source: Uniprot.org, NCBI)
Gene Name
LAMA2
Full Name
Laminin subunit alpha-2
Weight
343.905kDa
Alternative Names
LAMA2; Laminin alpha 2; Laminin M chain; laminin subunit alpha-2; laminin, alpha 2; Laminin-12 subunit alpha; Laminin-2 subunit alpha; LAMM; LAMMLaminin-4 subunit alpha; Merosin heavy chain; Merosin LAMA2 LAMM, MDC1A laminin subunit alpha 2 laminin subunit alpha-2|laminin M chain|laminin, alpha 2|laminin-12 subunit alpha|laminin-2 subunit alpha|laminin-4 subunit alpha|merosin heavy chain|mutant laminin subunit alpha 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LAMA2, check out the LAMA2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LAMA2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Laminin alpha-2 LAMA2 Antibody (A03287)
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No publications found for A03287
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Customer Reviews
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