Anti-Laminin 2 alpha/LAMA2 Antibody Picoband®

Product Name

Anti-Laminin 2 alpha/LAMA2 Antibody Picoband®

View all LAMA2 Antibodies

SKU/Catalog Number

PA2160
BA3201-2 is an alternative SKU for this antibody, used in previous lots.

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Laminin 2 alpha/LAMA2 Antibody catalog # PA2160. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Laminin 2 alpha/LAMA2 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2160)

Host

Rabbit

Contents

Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Laminin 2 alpha, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2160 is reactive to LAMA2 in Human, Mouse, Rat

Observed Molecular Weight

344 kDa

Calculated molecular weight

343.9 kDa

Background of LAMA2

Laminin, alpha-2, also known as LAMA2, is a protein that in humans is encoded by the LAMA2 gene. This gene is mapped to 6q22.33. Laminin, an extracellular protein, is a major component of the basement membrane. It is though to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2160 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Positive Control

WB: HELA Cell, A549 Cell, PANC Cell,

Validation Images & Assay Conditions

See full target information LAMA2

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