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Product Info Summary
| SKU: | A06359 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-LZTS1 Antibody (N-term)
SKU/Catalog Number
A06359
Size
80 µl
Description
Boster Bio Anti-LZTS1 Antibody (N-term) (Catalog # A06359). Tested in WB application(s). This antibody reacts with Human, Mouse.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-LZTS1 Antibody (N-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06359)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This LZTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human LZTS1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06359 is reactive to LZTS1 in Human, Mouse
Applications
A06359 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
66.613kDa
Background of LZTS1
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
Validation Images & Assay Conditions
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LZTS1 Antibody (N-term) western blot analysis in A2058 cell line and mouse brain tissue lysates (35ug/lane).This demonstrates the LZTS1 antibody detected the LZTS1 protein (arrow).
Protein Target Info & Infographic
Gene/Protein Information For LZTS1 (Source: Uniprot.org, NCBI)
Gene Name
LZTS1
Full Name
Leucine zipper putative tumor suppressor 1
Weight
66.613kDa
Superfamily
LZTS family
Alternative Names
F37; F37/esophageal cancer-related gene-coding leucine-zipper motifFez1; FEZ1leucine zipper putative tumor suppressor 1; leucine zipper, putative tumor suppressor 1 LZTS1 F37, FEZ1 leucine zipper tumor suppressor 1 leucine zipper putative tumor suppressor 1|F37/Esophageal cancer-related gene-coding leucine-zipper motif|leucine zipper, putative tumor suppressor 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LZTS1, check out the LZTS1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LZTS1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-LZTS1 Antibody (N-term) (A06359)
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No publications found for A06359
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Customer Reviews
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