Anti-M3K12 MAP3K12 Antibody

MAP3K12 antibody

Boster Bio Anti-M3K12 MAP3K12 Antibody catalog # A06739. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A06739
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, WB

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Product Name

Anti-M3K12 MAP3K12 Antibody

View all MAP3K12 Antibodies

SKU/Catalog Number

A06739

Size

100ul

Form

Liquid

Description

Boster Bio Anti-M3K12 MAP3K12 Antibody catalog # A06739. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-M3K12 MAP3K12 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06739)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human M3K12 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A06739 is reactive to MAP3K12 in Human, Mouse, Rat

Applications

A06739 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

93.219kDa

Background of MAP3K12

Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.

Nakajima T., J. Hum. Genet. 45:212-217(2000).
Nagase T., DNA Res. 2:37-43(1995).
Bechtel S., BMC Genomics 8:399-399(2007).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000 ELISA 1:5000-20000

Validation Images & Assay Conditions

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Gene/Protein Information For MAP3K12 (Source: Uniprot.org, NCBI)

Gene Name

MAP3K12

Full Name

Mitogen-activated protein kinase kinase kinase 12

Weight

93.219kDa

Superfamily

protein kinase superfamily

Alternative Names

DLKEC 2.7.11.25; Dual leucine zipper bearing kinase; EC 2.7.11; Leucine-zipper protein kinase; MAPK-upstream kinase; MEKK12; mitogen-activated protein kinase kinase kinase 12; Mixed lineage kinase; MUKdual leucine zipper kinase DLK; protein kinase MUK; ZPKleucine zipper protein kinase; ZPKP1 MAP3K12 DLK, MEKK12, MUK, ZPK, ZPKP1 mitogen-activated protein kinase kinase kinase 12 mitogen-activated protein kinase kinase kinase 12|MAPK-upstream kinase|dual leucine zipper bearing kinase|dual leucine zipper kinase DLK|leucine zipper protein kinase|mixed lineage kinase|protein kinase MUK

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MAP3K12, check out the MAP3K12 Infographic

MAP3K12 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MAP3K12: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A06739-100ul

100ul

$380

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$380.00

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