Zyxin Antibodies

AND ZYX ELISA kits, Zyxin Proteins

Many biological assays use antibodies to detect Zyxin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zyxin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zyxin antibodies...

We validate the specificity of these antibodies to Zyxin by testing them on tissues known to express ZYX positively and negatively. Browse below to find the ZYX antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Zyxin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the ZYX Western Blot Guide

ZYX Infographic by Boster Bio

All ZYX Products

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Product

Figures

Specificity

Applications

Price

Anti-Zyxin Monoclonal Antibody

Western blot analysis of Zyxin using anti-Zyxin antibody (M02365)

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M02365
100 μl

Zyxin (ZYX) (NM_003461) Human Over-expression Lysate

Human

$960
Cat # LS007791
20 µg, 100 µg

Zyxin (ZYX) (NM_001010972) Human Recombinant Protein

Coomassie blue staining of purified ZYX protein

$1249
Cat # PROTQ15942
20 µg

ZYX Overview

Facts about Zyxin.

ZYX 3D structure. Source: alphafold

Zyxin (ZYX)

Adhesion plaque protein. Binds alpha-actinin and the CRP protein.

Significant for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. Might be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression (By similarity).

Gene Information

Human
Gene Name:	ZYX
Uniprot:	Q15942
Entrez:	7791

Family

Belongs to:

zyxin/ajuba family

Alternative Names

CTCL tumor antigen se14-3; CTCL-associated antigen se14-3; cutaneous T-cell lymphoma associated antigen se14-3; Cutaneous T-cell lymphoma-associated antigen se14-3; KIAA1125; MGC31836; predicted protein of HQ2893; PRKCBP1; PRO2893; protein kinase C-binding protein 1; Rack7; RACK7protein kinase C binding protein 1; zinc finger MYND domain containing protein 8; Zinc finger MYND domain-containing protein 8; zinc finger, MYND-type containing 8; Zyx; Zyxin 2; Zyxin

Molecular Weight

Mass (kDA):
61.277 kDA

Genomic Context


Human

Location:	7q34
Sequence:	7; NC_000007.14 (143381345..143391111)

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Cell junction, focal adhesion. Associates with the actin cytoskeleton near the adhesion plaques. Enters the nucleus in the presence of HESX1.

Diseases

Tissue Adhesions
Neoplasms
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Lipoma
Cell Invasion
Malignant Neoplasm Of Breast
Carcinoma
Cell Transformation, Neoplastic
Neoplasm Invasiveness
Hypertrophy
Neoplasm Metastasis
Mammary Neoplasms

Leukemia
Melanoma
Infertility
Tumor Angiogenesis
Common Wart
Protrusion
Chromosomal Translocation

Interacting Proteins

IMP3
LASP1
LATS1
LIN7A
OPRM1

PDLIM5
PHF21A
VASP

Pathways

Cell Migration
Localization
Cell Motility
Cell Adhesion
Cell-cell Adhesion
Cell Cycle
Wound Healing
Cell Growth
Nuclear Export
Cell Proliferation
Endocytosis
Proteolysis
Fibroblast Migration

Spermatogenesis
Oncogenesis
Cell Death
Angiogenesis
Heart Development
Pachytene
Transport

PTMs

Phosphorylation
Cleavage

Reduction
Deacetylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZYX

References

PMID: 8940160 by Macalma T., et al. Molecular characterization of human zyxin.

PMID: 8917469 by Zumbrunn J., et al. A zyxin-related protein whose synthesis is reduced in virally transformed fibroblasts.