Product Info Summary
SKU: | M05037 |
---|---|
Size: | 80 µl |
Reactive Species: | Human |
Host: | Mouse |
Application: | WB |
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Product info
Product Name
Anti-MAGED1 Antibody (Center)
View all NRAGE/MAGED1 Antibodies
SKU/Catalog Number
M05037
Size
80 µl
Description
Boster Bio Anti-MAGED1 Antibody (Center) (Catalog # M05037). Tested in WB application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-MAGED1 Antibody (Center) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M05037)
Host
Mouse
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Monoclonal
Clone Number
1305CT862.157.127
Isotype
IgG1,κ
Immunogen
This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the Central region of human MAGED1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M05037 is reactive to MAGED1 in Human
Applications
M05037 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
86.161kDa
Background of NRAGE/MAGED1
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds NGFR/p75NTR and antagonizes its association with NTRK1/TrkA, inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate TP53/p53 transcriptional activity and inhibit cell proliferation. Enhances TP53 phosphorylation and accumulation. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of lysates from Jurkat, 293 cell line (from left to right), using MAGED1 Antibody (Center). M05037 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L (HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35μg per lane.
Protein Target Info & Infographic
Gene/Protein Information For MAGED1 (Source: Uniprot.org, NCBI)
Gene Name
MAGED1
Full Name
Melanoma-associated antigen D1
Weight
86.161kDa
Alternative Names
Dlxin-1; MAGE tumor antigen CCF; MAGED1; melanoma antigen family D, 1; melanoma-associated antigen D1; Neurotrophin receptor-interacting MAGE homolog; NRAGE MAGE-D1 antigen; NRAGE MAGED1 DLXIN-1, NRAGE MAGE family member D1 melanoma-associated antigen D1|MAGE tumor antigen CCF|MAGE-D1 antigen|melanoma antigen family D, 1|melanoma antigen family D1|neurotrophin receptor-interacting MAGE homolog
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MAGED1, check out the MAGED1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MAGED1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MAGED1 Antibody (Center) (M05037)
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No publications found for M05037
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