Anti-MAP7D1 Antibody

Product Name

Anti-MAP7D1 Antibody

View all MAP7D1 Antibodies

SKU/Catalog Number

A13074

Size

100ul

Form

Liquid

Description

Boster Bio Anti-MAP7D1 Antibody catalog # A13074. Tested in WB applications. This antibody reacts with Human,Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MAP7D1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13074)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human CARD 6

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A13074 is reactive to MAP7D1 in Human, Mouse

Applications

A13074 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

92.82kDa

Background of MAP7D1

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway By similarity.

Hu P., Mol. Cell. Biol. 22:8044-8055(2002).
Hirosawa M., DNA Res. 8:1-9(2001).
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-MAP7D1 Antibody A13074

Western blot analysis of extracts of various cell lines

Gene/Protein Information For MAP7D1 (Source: Uniprot.org, NCBI)

Alternative Names

MAP7 domain containing 1 MAP7D1 PARCC1, RPRC1 MAP7 domain containing 1 MAP7 domain-containing protein 1|arginine/proline rich coiled-coil 1|arginine/proline-rich coiled-coil domain-containing protein 1|proline arginine rich coiled coil 1|proline/arginine-rich coiled-coil domain-containing protein 1

For more info on MAP7D1, check out the MAP7D1 Infographic

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In this infographic, you will see the following information for MAP7D1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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