Product Info Summary
SKU: | A04564 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC |
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Product info
Product Name
Anti-MARK1/2/3/4 (N211) Antibody
SKU/Catalog Number
A04564
Size
100ul
Form
Liquid
Description
Boster Bio Anti-MARK1/2/3/4 (N211) Antibody catalog # A04564. Tested in IHC,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MARK1/2/3/4 (N211) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04564)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Pax-1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04564 is reactive to MARK1 in Human, Mouse, Rat
Applications
A04564 is guaranteed for IF, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
89.003kDa
Background of MARK1
Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.
Florindo C.S., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Devroe E., J. Biol. Chem. 279:24444-24451(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of MARK1 using Anti-MARK1/2/3/4 (N211) Antibody (A04564).
Immunohistochemistry (IHC) analyzes of MARK1/2/3/4 (N211) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For MARK1 (Source: Uniprot.org, NCBI)
Gene Name
MARK1
Full Name
Serine/threonine-protein kinase MARK1
Weight
89.003kDa
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.11; EC 2.7.11.1; KIAA1477serine/threonine-protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1MGC126512; MARKMGC126513 MARK1 MARK, Par-1c, Par1c microtubule affinity regulating kinase 1 serine/threonine-protein kinase MARK1|MAP/microtubule affinity-regulating kinase 1|PAR1 homolog c
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MARK1, check out the MARK1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MARK1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MARK1/2/3/4 (N211) Antibody (A04564)
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No publications found for A04564
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