Anti-MRF2 ARID5B Antibody

Product Name

Anti-MRF2 ARID5B Antibody

View all Arid5b Antibodies

SKU/Catalog Number

A02880

Size

100 µg

Form

Liquid

Description

Boster Bio Anti-MRF2 ARID5B Antibody (Catalog# A02880). Tested in WB application(s). This antibody reacts with Human.

Storage & Handling

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Cite This Product

Anti-MRF2 ARID5B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02880)

Host

Rabbit

Contents

100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A partial length recombinant MRF2 protein (amino acids 430-621)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A02880 is reactive to Arid5b in Human

Applications

A02880 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

131.837kDa

Background of Arid5b

FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is ubiquitously expressed. Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot: 1-2 µg/ml

Validation Images & Assay Conditions

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Expression analysis of MRF2. Anti-MRF2 antibody was used at 1 &mu

Gene/Protein Information For Arid5b (Source: Uniprot.org, NCBI)

Alternative Names

ARID domain-containing protein 5B; AT rich interactive domain 5B (MRF1-like); DESRTAT-rich interactive domain-containing protein 5B; FLJ21150; modulator recognition factor 2 (MRF2); Modulator recognition factor 2; MRF-2; MRF2MRF1-like protein Arid5b|4930580B11, 5430435G07Rik, AI467247, Des, Desrt, Mrf, Mrf2, Mrf2alpha, Mrf2be, Mrf2beta|AT rich interactive domain 5B (MRF1-like)|AT-rich interactive domain-containing protein 5B|ARID class DNA binding protein|ARID domain-containing protein 5B|AT rich interactive domain 5B (Mrf1 like)|MRF-2|developmentally and sexually retarded with transient immune abnormalities protein|modulator recognition factor 2|modulator recognition factor protein 2

For more info on Arid5b, check out the Arid5b Infographic

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In this infographic, you will see the following information for Arid5b: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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