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Product Info Summary
| SKU: | M01911-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Mouse |
| Host: | Rat |
| Application: | Flow Cytometry, IHC-F, ICC |
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Product info
Product Name
Anti-Ms CD49e Purified Itga5 Monoclonal Antibody
SKU/Catalog Number
M01911-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Ms CD49e Purified Itga5 Monoclonal Antibody (Catalog# M01911-1). Tested in ICC, Flow Cytometry, IHC-F application(s). This antibody reacts with Mouse.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Ms CD49e Purified Itga5 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01911-1)
Host
Rat
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
5H10-27 (MFR5)
Isotype
Rat IgG2a kappa
Immunogen
C57BL/6 x A/J)F1 murine mast cell line. The rat monoclonal antibody 5H10-27 (MFR5) recognizes an extracellular epitope of murine CD49e, a 135 kDa protein serving as VLA-5 alpha chain, expressed on thymocytes, activated T cells, splenic B cells, and mast cells.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01911-1 is reactive to ITGA5 in Mouse
Applications
M01911-1 is guaranteed for Flow Cytometry, IHC-F, ICC Boster Guarantee
Observed Molecular Weight
19 kDa
Calculated molecular weight
114.536kDa
Background of ITGA5
CD49e, the alpha 5 integrin, noncovalently associates with the beta 1integrin (CD29) to form VLA-5 integrin complex. CD49e itself is composed of two disulfide-linked chains of 135 kDa and 25 kDa. VLA-5 binds to RGD sequence of fibronectin, and to neural adhesion molecule L1. It is important in maintaining the integrity of endothelial monolayers, in monocyte migration into the extracellular tissues, and it also provides a co-stimulatory signal to T cells and enhances receptor and complement receptor-mediated phagocytosis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml.
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For ITGA5 (Source: Uniprot.org, NCBI)
Gene Name
ITGA5
Full Name
Integrin alpha-5
Weight
114.536kDa
Superfamily
integrin alpha chain family
Alternative Names
Integrin alpha 5 beta 1; VLA-5 ITGA5 CD49e, FNRA, VLA-5, VLA5A integrin subunit alpha 5 integrin alpha-5|CD49 antigen-like family member E|ITGA5/SLC9B1 fusion|fibronectin receptor subunit alpha|fibronectin receptor, alpha polypeptide|fibronectin receptor, alpha subunit|integrin alpha-F|integrin, alpha 5 (fibronectin receptor, alpha polypeptide)|very late activation protein 5, alpha subunit
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ITGA5, check out the ITGA5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ITGA5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ms CD49e Purified Itga5 Monoclonal Antibody (M01911-1)
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No publications found for M01911-1
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