Product Info Summary
SKU: | A03631 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | Flow Cytometry, IP, IF, IHC, ICC, WB |
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Product info
Product Name
Anti-MTCO2 Antibody
SKU/Catalog Number
A03631
Size
100ul
Form
Liquid
Description
Boster Bio Anti-MTCO2 Antibody catalog # A03631. Tested in WB,ICC/IF,IHC,IP,Flow Cytometry applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MTCO2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03631)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human BLNK around the phosphorylation site of Y96.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03631 is reactive to MT-CO2 in Human
Applications
A03631 is guaranteed for Flow Cytometry, IP, IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
25.565kDa
Background of MT-CO2
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis By similarity. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
Benovic J.L., J. Biol. Chem. 268:19521-19527(1993).
Haribabu B., Proc. Natl. Acad. Sci. U.S.A. 90:9398-9402(1993).
Stoffel R.H., J. Biol. Chem. 269:27791-27794(1994).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1,000-1:2,000
ICC: 1:50-1:200
IHC: 1:50-1:200
FC: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunocytochemistry staining of MT-CO2 using Anti-MTCO2 Antibody (A03631).
ICC staining MTCO2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehydeClick image to see more details
Figure 1. Western blotting validation for Anti-MTCO2 Antibody A03631
Western blot analysis of MTCO2 on different lysates using anti-MTCO2 antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For MT-CO2 (Source: Uniprot.org, NCBI)
Gene Name
MT-CO2
Full Name
Cytochrome c oxidase subunit 2
Weight
25.565kDa
Superfamily
cytochrome c oxidase subunit 2 family
Alternative Names
COII; COX2; COXII; Cytochrome C Oxidase II; Cytochrome C Oxidase Polypeptide II; Cytochrome C Oxidase Subunit II; EC 1.9.3.1; Mitochondrially Encoded Cytochrome C Oxidase II; MTCO2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MT-CO2, check out the MT-CO2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MT-CO2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MTCO2 Antibody (A03631)
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No publications found for A03631
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Customer Reviews
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